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Stockholders' Equity - Shares Reserved For Future Issuances (Detail) - shares	Jun. 30, 2022	Dec. 31, 2021
Class Of Stock [Line Items]
Common Stock, Capital Shares Reserved for Future Issuance	74,310,805	55,139,084
Exercise of Common Stock Warrants and Pre-funded Warrants
Class Of Stock [Line Items]
Common Stock, Capital Shares Reserved for Future Issuance	38,382,647	20,602,244
LPC Purchase Agreement [Member]
Class Of Stock [Line Items]
Common Stock, Capital Shares Reserved for Future Issuance	30,000,000	30,000,000
2012 Stock Option And Grant Plan [Member] | 2012 Stock Incentive Plan [Member]
Class Of Stock [Line Items]
Common Stock, Capital Shares Reserved for Future Issuance	663,089	665,720
2019 Stock Option And Grant Plan [Member] | 2019 Stock Incentive Plan [Member]
Class Of Stock [Line Items]
Common Stock, Capital Shares Reserved for Future Issuance	4,543,352	3,400,489
2019 Stock Option And Grant Plan [Member] | 2019 Employee Stock Purchase Plan [Member]
Class Of Stock [Line Items]
Common Stock, Capital Shares Reserved for Future Issuance	721,717	470,631

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Aggregate number of common shares reserved for future issuance.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02.29)
-URI https://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682

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