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Segments | 6 Months Ended
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Jun. 30, 2026
Segment Reporting [Abstract] |
Segments | 9. Segments The Company's single reportable segment is the business of developing and commercializing the investigational therapy Haduvio (oral nalbuphine ER) for the treatment of chronic cough in patients with IPF, non-IPF ILD, and RCC. The accounting policies of the segment are described in Note 2 of the notes to the Condensed Consolidated Financial Statements included in this Quarterly Report on Form 10-Q. The following table presents reportable segment loss, including significant expense categories, attributable to the Company’s reportable segment for the periods presented:
|  | Three Months Ended June 30, |  |  | Six Months Ended June 30, |
|  | 2026 |  |  | 2025 |  |  | 2026 |  |  | 2025 |
Chronic cough in IPF clinical trial expense |  | $ | 4,347 |  |  | $ | 3,039 |  |  | $ | 6,034 |  |  | $ | 5,921 |
Refractory chronic cough clinical trial expense |  |  | 2,028 |  |  |  | 434 |  |  |  | 3,106 |  |  |  | 1,252 |
Clinical trial material |  |  | 2,351 |  |  |  | 330 |  |  |  | 3,904 |  |  |  | 564 |
Other clinical trials and studies 1 |  |  | 1,144 |  |  |  | 1,269 |  |  |  | 2,443 |  |  |  | 1,317 |
Other clinical development expenses 2 |  |  | 1,848 |  |  |  | 1,861 |  |  |  | 3,371 |  |  |  | 3,279 |
Employee compensation (excluding stock compensation expense) |  |  | 3,347 |  |  |  | 2,818 |  |  |  | 6,506 |  |  |  | 5,775 |
Stock-based compensation expense |  |  | 3,272 |  |  |  | 1,384 |  |  |  | 5,463 |  |  |  | 2,592 |
Other segment items 3 |  |  | 2,156 |  |  |  | 2,573 |  |  |  | 4,554 |  |  |  | 4,473 |
Interest income, net |  |  | (2,696 | ) |  |  | (1,407 | ) |  |  | (4,392 | ) |  |  | (2,532 | )
Net loss |  | $ | 17,797 |  |  | $ | 12,301 |  |  | $ | 30,989 |  |  | $ | 22,641 |
(1) Includes expense related to the Company’s Phase 1 NDA supportive studies (2) Includes expense related to general research and development activities, regulatory, medical affairs, and quality assurance. (3) Includes general administrative expense, other (expense) income, net and income tax benefit.

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