v3.23.1
Commitments and Contingencies (Details)
 1 Months Ended 3 Months Ended 12 Months Ended
Dec. 31, 2008
USD ($)
shares
Mar. 31, 2023
USD ($)
shares
Mar. 31, 2022
USD ($)
Dec. 31, 2021
USD ($)
Dec. 31, 2020
USD ($)
Dec. 31, 2014
shares
Feb. 08, 2023
USD ($)
Feb. 08, 2023
EUR (€)
Commitments and Contingencies (Details) [Line Items]                
Reimbursement costs         $ 30,000      
Reimburse costs       $ 41,000        
Aggregate deposit amount   $ 126,000            
Cash amount             $ 50,000 € 10,000
Security deposits   126,000            
Deposits   $ 50,000            
Amount of initial licensing fee $ 325,000              
Shares of common stock (in Shares) | shares 7,996              
Number of shares issuable (in Shares) | shares   29,109            
Number of shares released in escrow (in Shares) | shares           7,277    
Number of share held In escrow of common stock (in Shares) | shares   21,832            
Maximum aggregate amount of cash payments   $ 3,000,000            
Balance of cash payments due upon achievement of milestones   $ 2,500,000 $ 2,500,000          
Euro [Member]                
Commitments and Contingencies (Details) [Line Items]                
Cash amount | €               € 36,000
NDP [Member]                
Commitments and Contingencies (Details) [Line Items]                
Equity interest percentage 5.00%