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Commitments (Details)
€ in Thousands, $ in Thousands
 1 Months Ended 3 Months Ended 6 Months Ended 10 Months Ended 12 Months Ended 36 Months Ended
Feb. 03, 2020
USD ($)
May 31, 2021
USD ($)
Mar. 31, 2021
USD ($)
Jan. 31, 2019
USD ($)
patient
Jul. 31, 2018
Mar. 31, 2021
USD ($)
Jun. 30, 2021
EUR (€)
Dec. 31, 2021
USD ($)
Dec. 31, 2021
USD ($)
lease_contract
Dec. 31, 2021
EUR (€)
lease_contract
Dec. 31, 2021
EUR (€)
Dec. 31, 2020
EUR (€)
Disclosure of contingent liabilities [line items]                        
Number of short term leases | lease_contract                 1 1    
Annual short term lease expense | €                   € 140    
Annual lease expense | €                   10    
Prepaid expenses | €                   2,213 € 2,213 € 2,217
MD Anderson Cancer Center, NBTXR3                        
Disclosure of contingent liabilities [line items]                        
Number of patients | patient       340                
Contractual capital commitments | $       $ 11,000                
Upfront payment | $ $ 1,000     $ 1,000                
Milestone payment, deferment period       6 months                
Research expense since start of collaboration | €                     1,800  
Prepaid expenses | €                   1,000 1,000 € 1,600
MD Anderson Cancer Center, NBTXR3 | Bottom of range                        
Disclosure of contingent liabilities [line items]                        
Milestone payment increase | $                 $ 2,200      
MD Anderson Cancer Center, NBTXR3 | Top of range                        
Disclosure of contingent liabilities [line items]                        
Milestone payment increase | $                 16,400      
Termination of PharmaEngine License and Collaboration Agreement, NBTXR3                        
Disclosure of contingent liabilities [line items]                        
Upfront payment   $ 4,000 $ 2,500       € 5,400 $ 6,500 $ 6,500 5,400    
Milestone payment upon receipt of clinical study reports | $     1,000     $ 1,000            
Milestone payment upon second regulatory approval | $     $ 5,000     $ 5,000            
Royalties agreement, period     10 years     10 years            
EIB fixed rate loan                        
Disclosure of contingent liabilities [line items]                        
Royalties agreement, period         6 years              
Minimum | EIB fixed rate loan                        
Disclosure of contingent liabilities [line items]                        
Estimated financial effect of contingent liabilities | €                   € 35,000 € 35,000