v3.19.1
Income Taxes - Schedule of Effective Income Tax Rate Reconciliation (Detail)
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Income Tax Disclosure [Abstract]    
Federal statutory income tax rate 21.00% 34.00%
State taxes, net of federal benefit 6.10% 3.00%
Federal and state research and development tax credits 9.60% 13.70%
Nondeductible items (0.80%) (1.70%)
2017 TCJA   (26.90%)
Stock-based compensation 4.40% (2.60%)
Other 0.20% 0.30%
Change in valuation allowance (40.50%) (19.80%)
Effective income tax rate 0.00% 0.00%