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Sale of future royalties - Liability Activity (Details) - USD ($)
$ in Thousands
 6 Months Ended 9 Months Ended
Jul. 02, 2019
Jun. 30, 2023
Jun. 30, 2022
Sep. 30, 2014
Liability Related To Sale Of Future Royalties [Roll Forward]        
Net liability related to sale of future royalties - beginning balance   $ 10,365 $ 16,296  
Non-cash royalty revenue   (1,944) (3,048)  
Non-cash interest expense   366 985  
Net liability related to sale of future royalties - ending balance   8,787 $ 14,233  
ONPATTRO        
Research and Development Arrangement, Contract to Perform for Others [Line Items]        
Royalty interest sold, annual revenue threshold of highest tier $ 500,000 $ 500,000   $ 500,000