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Accounts payable and accrued liabilities | 3 Months Ended
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Mar. 31, 2025
Payables and Accruals [Abstract] |
Accounts payable and accrued liabilities |
| March 31, 2025 |  | December 31, 2024
| (in thousands)
Trade accounts payable | $ | 2,240 |  |  | $ | 2,316 |
Research and development accruals | 1,173 |  |  | 3,393 |
Professional fee accruals | 2,237 |  |  | 691 |
Payroll accruals | 494 |  |  | 1,164 |
Restructuring liabilities | 5,965 |  |  | — |
Total accounts payable and accrued liabilities | $ | 12,109 |  |  | $ | 7,564 |
In March 2025, the Company’s Board of Directors (the Board) took action to reduce the Company’s workforce by 57%, resulting in a total workforce after reductions of 19 employees. The Board also decided to exit the Company’s corporate headquarters in Warminster, Pennsylvania and to discontinue in-house scientific research. As a result, the Company recorded a one-time restructuring charge of $12.4 million in the first quarter of 2025, of which there was $5.6 million in severance and benefit costs and $0.4 million of lease-related operation expenses accrued as of March 31, 2025.

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