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Accounts payable and accrued liabilities
 3 Months Ended
Mar. 31, 2025
Payables and Accruals [Abstract]  
Accounts payable and accrued liabilities
 March 31, 2025December 31, 2024
(in thousands)
Trade accounts payable$2,240 $2,316 
Research and development accruals1,173 3,393 
Professional fee accruals2,237 691 
Payroll accruals494 1,164 
Restructuring liabilities5,965 — 
Total accounts payable and accrued liabilities$12,109 $7,564 
In March 2025, the Company’s Board of Directors (the Board) took action to reduce the Company’s workforce by 57%, resulting in a total workforce after reductions of 19 employees. The Board also decided to exit the Company’s corporate headquarters in Warminster, Pennsylvania and to discontinue in-house scientific research. As a result, the Company recorded a one-time restructuring charge of $12.4 million in the first quarter of 2025, of which there was $5.6 million in severance and benefit costs and $0.4 million of lease-related operation expenses accrued as of March 31, 2025.