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Shareholders’ equity
 3 Months Ended
Mar. 31, 2025
Stockholders' Equity Note [Abstract]  
Shareholders’ equity Shareholders’ equity
Authorized share capital
The Company’s authorized share capital consists of an unlimited number of common shares and preferred shares, without par value, and 1,164,000 Series A participating convertible preferred shares, without par value.
Open Market Sale Agreement

Effective March 26, 2025, the Company terminated its Open Market Sale Agreement with Jefferies LLC (Jefferies) dated December 20, 2018, as amended (the Sale Agreement), under which the Company could offer and sell common shares, from time to time.

Prior to the termination of the Sale Agreement, the Company did not issue any common shares pursuant to the Sale Agreement during the three months ended March 31, 2025. During the three months ended March 31, 2024, the Company issued 8,666,077 common shares pursuant to the Sale Agreement, resulting in net proceeds of $21.8 million.

Stock-based compensation

The table below summarizes information about the Company’s stock-based compensation for the three months ended March 31, 2025 and 2024 and the expense recognized in the condensed consolidated statements of operations:
Three Months Ended March 31,
20252024
(in thousands, except share and per share data)
Stock options
Options granted during period3,943,722 3,738,800 
Weighted average exercise price$3.31 $2.40 
Restricted stock units (RSUs)
Restricted stock units granted during period901,900 1,316,200 
Grant date fair value$3.29 $2.40 
Stock compensation expense
Research and development$555 $1,041 
General and administrative738 973 
Total stock compensation expense$1,293 $2,014