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Segment Reporting
 3 Months Ended
Mar. 31, 2025
Segment Reporting [Abstract]  
Segment Reporting Disclosure Segment Reporting
The Company has one reportable segment. The Company’s chief operating decision maker is the Chief Executive Officer and President. The accounting policies of the single segment are the same as those described in the summary of significant accounting policies. The chief operating decision maker assesses performance for the single segment and decides how to allocate resources based on net loss that also is reported on the condensed and consolidated statements of operations and comprehensive loss as consolidated net loss. The chief operating decision maker uses net loss to monitor budget versus actual results and to evaluate the overall cash burn of the business.

Three months ended March 31,
20252024
Revenue$1,764 $1,532 
Less:
Research and development employee expense, lab supplies and overhead4,436 7,100 
Imdusiran IM-PROVE I, II & III clinical trials expense2,384 5,389 
AB-101-001 Phase 1a/1b clinical trial expense1,899 2,810 
Other early research and development programs expense240 104 
General and administrative expense5,832 5,312 
Restructuring expense12,373 — 
Other segment expense (1)
323 237 
Add:
Interest income1,197 1,545 
Segment net loss$(24,526)$(17,875)
Adjustments and reconciling items— — 
Consolidated net loss$(24,526)$(17,875)
(1) Other segment expense includes the change in the fair value of contingent consideration, non-cash interest expenses and foreign currency exchange gains and losses.