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Collaborations, contracts and licensing agreements (Tables)

6 Months Ended

Jun. 30, 2025

Revenue from Contract with Customer [Abstract]

Schedule of deferred collaborations and contracts revenue

The following table outlines the transaction price and the changes to the related liability balance:

			Transaction Price						Cumulative Collaboration Revenue Recognized						Deferred License Revenue
			(in thousands)
Combined performance obligation			$	50,445					$	50,445					$	—
Less contract asset															—
Total deferred license revenue															$	—

Summary of collaborations

Revenues are summarized in the following table:

			Three Months Ended June 30,												Six Months Ended June 30,
			2025						2024						2025						2024
			(in thousands)												(in thousands)
Revenue from collaborations and licenses
Acuitas Therapeutics, Inc.			$	591					$	642					$	1,095					$	1,337
Qilu Pharmaceutical Co., Ltd.			9,622						513						10,434						757
Non-cash royalty revenue
Alnylam Pharmaceuticals, Inc.			526						571						974						1,164
Total revenue			$	10,739					$	1,726					$	12,503					$	3,258

X

- Definition

Tabular disclosure of receivable, contract asset, and contract liability from contract with customer. Includes, but is not limited to, change in contract asset and contract liability.

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 606
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 10
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479806/606-10-50-10

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- References

No definition available.

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X

- Definition

Tabular disclosure of collaborative arrangement and arrangement other than collaborative applicable to revenue-generating activity or operations.

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 808
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 1
-Subparagraph (d)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479402/808-10-50-1

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