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v3.25.3

Condensed Consolidated Statements of Cash Flow (Unaudited) - USD ($) $ in Thousands | 9 Months Ended
--- | ---
Sep. 30, 2025 | Sep. 30, 2024
OPERATING ACTIVITIES |  |
Net Income (Loss) | $ (29,745) | $ (57,388)
Non-cash items: |  |
Depreciation | 352 | 1,047
Loss on impairment of leasehold improvements and lab equipment | 2,811 | 167
Stock-based compensation expense | 5,691 | 7,354
Change in fair value of contingent consideration | 827 | 735
Non-cash royalty revenue | (1,223) | (1,736)
Non-cash interest expense | 78 | 98
Net accretion and amortization of investments in marketable securities | (1,927) | (2,212)
Net change in operating items: |  |
Accounts receivable | 1,504 | 168
Prepaid expenses and other assets | 400 | 1,145
Accounts payable and accrued liabilities | (2,911) | (2,727)
Change in deferred license revenue | (10,434) | (880)
Other liabilities | (380) | (306)
Net cash used in operating activities | (34,957) | (54,535)
INVESTING ACTIVITIES |  |
Purchase of investments in marketable securities | (114,514) | (98,318)
Proceeds from sale of property and equipment | 9 | 0
Disposition of investments in marketable securities | 131,446 | 107,951
Acquisition of property and equipment | 0 | (96)
Net cash provided by investing activities | 16,941 | 9,537
FINANCING ACTIVITIES |  |
Issuance of common shares pursuant to the Open Market Sale Agreement | 0 | 44,124
Issuance of common shares pursuant to exercise of stock options | 3,900 | 6,055
Issuance of common shares pursuant to ESPP | 181 | 396
Net cash provided by financing activities | 4,081 | 50,575
Effect of foreign exchange rate changes on cash and cash equivalents | 13 | (16)
(Decrease) / Increase in cash and cash equivalents | (13,922) | 5,561
Cash and cash equivalents, beginning of period | 36,330 | 26,285
Cash and cash equivalents, end of period | $ 22,408 | $ 31,846

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