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v3.25.3

Condensed Consolidated Statement of Stockholders’ Equity (Unaudited) - USD ($) $ in Thousands | Total | Common Shares | Additional Paid-In Capital | Deficit | Accumulated Other Comprehensive Loss
--- | --- | --- | --- | --- | ---
Beginning balance (in shares) at Dec. 31, 2023 |  | 169,867,414 |  |  |
Beginning balance at Dec. 31, 2023 | $ 106,018 | $ 1,349,821 | $ 81,270 | $ (1,276,652) | $ (48,421)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |
Stock-based compensation expense | 2,014 |  | 2,014 |  |
Issuance of common shares pursuant to the Open Market Sale Agreement (in shares) |  | 8,666,077 |  |  |
Issuance of common shares pursuant to the Open Market Sale Agreement | 21,765 | $ 21,765 |  |  |
Issuance of common shares pursuant to exercise of options (in shares) |  | 1,126,691 |  |  |
Issuance of common shares pursuant to ESPP | 2,454 | $ 4,268 | (1,814) |  |
Issuance of common shares pursuant to ESPP (in shares) |  | 121,563 |  |  |
Issuance of common shares pursuant to ESPP | 211 | $ 271 | (60) |  |
Issuance of common shares upon vesting of RSUs |  | 410,482 |  |  |
Issuance of common shares upon vesting of RSUs | 0 | $ 1,190 | (1,190) |  |
Unrealized loss on available-for-sale securities | 50 |  |  |  | 50
Net loss | (17,875) |  |  | (17,875) |
Ending balance (in shares) at Mar. 31, 2024 |  | 180,192,227 |  |  |
Ending balance at Mar. 31, 2024 | 114,637 | $ 1,377,315 | 80,220 | (1,294,527) | (48,371)
Beginning balance (in shares) at Dec. 31, 2023 |  | 169,867,414 |  |  |
Beginning balance at Dec. 31, 2023 | 106,018 | $ 1,349,821 | 81,270 | (1,276,652) | (48,421)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |
Net loss | (57,388) |  |  |  |
Ending balance (in shares) at Sep. 30, 2024 |  | 189,438,135 |  |  |
Ending balance at Sep. 30, 2024 | 106,890 | $ 1,407,595 | 81,425 | (1,334,040) | (48,090)
Beginning balance (in shares) at Mar. 31, 2024 |  | 180,192,227 |  |  |
Beginning balance at Mar. 31, 2024 | 114,637 | $ 1,377,315 | 80,220 | (1,294,527) | (48,371)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |
Stock-based compensation expense | 3,180 |  | 3,180 |  |
Issuance of common shares pursuant to the Open Market Sale Agreement (in shares) |  | 7,833,922 |  |  |
Issuance of common shares pursuant to the Open Market Sale Agreement | 22,359 | $ 22,359 |  |  |
Issuance of common shares pursuant to exercise of options (in shares) |  | 712,895 |  |  |
Issuance of common shares pursuant to ESPP | 2,011 | $ 3,660 | (1,649) |  |
Unrealized loss on available-for-sale securities | 63 |  |  |  | 63
Net loss | (19,796) |  |  | (19,796) |
Ending balance (in shares) at Jun. 30, 2024 |  | 188,739,044 |  |  |
Ending balance at Jun. 30, 2024 | 122,454 | $ 1,403,334 | 81,751 | (1,314,323) | (48,308)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |
Stock-based compensation expense | 2,160 |  | 2,160 |  |
Issuance of common shares pursuant to the Open Market Sale Agreement (in shares) |  | 593,321 |  |  |
Issuance of common shares pursuant to the Open Market Sale Agreement | 1,590 | $ 3,996 |  |  |
Issuance of common shares pursuant to exercise of options (in shares) |  | 105,770 |  |  |
Issuance of common shares pursuant to ESPP | 185 | $ 265 | (80) |  |
Unrealized loss on available-for-sale securities | 218 |  |  |  | 218
Net loss | (19,717) |  |  | (19,717) |
Ending balance (in shares) at Sep. 30, 2024 |  | 189,438,135 |  |  |
Ending balance at Sep. 30, 2024 | $ 106,890 | $ 1,407,595 | 81,425 | (1,334,040) | (48,090)
Beginning balance (in shares) at Dec. 31, 2024 | 189,963,492 | 189,963,492 |  |  |
Beginning balance at Dec. 31, 2024 | $ 97,366 | $ 1,410,025 | 82,048 | (1,346,572) | (48,135)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |
Stock-based compensation expense | 3,564 |  | 3,564 |  |
Issuance of common shares pursuant to exercise of options (in shares) |  | 892,857 |  |  |
Issuance of common shares pursuant to ESPP | 2,653 | $ 4,616 | (1,963) |  |
Issuance of common shares pursuant to ESPP (in shares) |  | 44,541 |  |  |
Issuance of common shares pursuant to ESPP | 131 | $ 173 | (42) |  |
Issuance of common shares upon vesting of RSUs |  | 580,584 |  |  |
Issuance of common shares upon vesting of RSUs | 0 | $ 1,518 | (1,518) |  |
Unrealized loss on available-for-sale securities | (31) |  |  |  | (31)
Net loss | (24,526) |  |  | (24,526) |
Ending balance (in shares) at Mar. 31, 2025 |  | 191,481,474 |  |  |
Ending balance at Mar. 31, 2025 | $ 79,157 | $ 1,416,332 | 82,089 | (1,371,098) | (48,166)
Beginning balance (in shares) at Dec. 31, 2024 | 189,963,492 | 189,963,492 |  |  |
Beginning balance at Dec. 31, 2024 | $ 97,366 | $ 1,410,025 | 82,048 | (1,346,572) | (48,135)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |
Net loss | $ (29,745) |  |  |  |
Ending balance (in shares) at Sep. 30, 2025 | 191,953,665 | 191,953,665 |  |  |
Ending balance at Sep. 30, 2025 | $ 77,399 | $ 1,418,560 | 83,285 | (1,376,317) | (48,129)
Beginning balance (in shares) at Mar. 31, 2025 |  | 191,481,474 |  |  |
Beginning balance at Mar. 31, 2025 | 79,157 | $ 1,416,332 | 82,089 | (1,371,098) | (48,166)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |
Stock-based compensation expense | 864 |  | 864 |  |
Issuance of common shares pursuant to exercise of options (in shares) |  | 160,037 |  |  |
Issuance of common shares pursuant to ESPP | 453 | $ 778 | (325) |  |
Unrealized loss on available-for-sale securities | (21) |  |  |  | (21)
Net loss | 2,523 |  |  | 2,523 |
Ending balance (in shares) at Jun. 30, 2025 |  | 191,641,511 |  |  |
Ending balance at Jun. 30, 2025 | 82,976 | $ 1,417,110 | 82,628 | (1,368,575) | (48,187)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |
Stock-based compensation expense | 1,263 |  | 1,263 |  |
Issuance of common shares pursuant to exercise of options (in shares) |  | 296,202 |  |  |
Issuance of common shares pursuant to ESPP | 794 | $ 1,371 | (577) |  |
Issuance of common shares pursuant to ESPP (in shares) |  | 15,952 |  |  |
Issuance of common shares pursuant to ESPP | 50 | $ 79 | (29) |  |
Unrealized loss on available-for-sale securities | 58 |  |  |  | 58
Net loss | $ (7,742) |  |  | (7,742) |
Ending balance (in shares) at Sep. 30, 2025 | 191,953,665 | 191,953,665 |  |  |
Ending balance at Sep. 30, 2025 | $ 77,399 | $ 1,418,560 | $ 83,285 | $ (1,376,317) | $ (48,129)

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