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Accounts payable and accrued liabilities | 9 Months Ended
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Sep. 30, 2025
Payables and Accruals [Abstract] |
Accounts payable and accrued liabilities | Accounts payable and accrued liabilities Accounts payable and accrued liabilities are comprised of the following:
| September 30, 2025 |  | December 31, 2024
| (in thousands)
Trade accounts payable | $ | 1,011 |  |  | $ | 2,316 |
Research and development accruals | 413 |  |  | 691 |
Professional fee accruals | 443 |  |  | 1,164 |
Payroll accruals | 2,023 |  |  | 3,393 |
Restructuring liabilities | 763 |  |  | — |
Total accounts payable and accrued liabilities | $ | 4,653 |  |  | $ | 7,564 |
In March 2025, the Company’s Board of Directors (the Board) took action to reduce the Company’s workforce by 57%. The Board also decided to exit the Company’s corporate headquarters in Warminster, Pennsylvania and to discontinue in-house scientific research. As a result, the Company recorded a one-time restructuring charge of $12.4 million in the first quarter of 2025, of which there was $0.5 million in severance and benefit costs and $0.3 million of lease-related operation expenses accrued as of September 30, 2025.

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