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Accounts payable and accrued liabilities
 9 Months Ended
Sep. 30, 2025
Payables and Accruals [Abstract]  
Accounts payable and accrued liabilities Accounts payable and accrued liabilities
Accounts payable and accrued liabilities are comprised of the following:
 September 30, 2025December 31, 2024
(in thousands)
Trade accounts payable$1,011 $2,316 
Research and development accruals413 691 
Professional fee accruals443 1,164 
Payroll accruals2,023 3,393 
Restructuring liabilities763 — 
Total accounts payable and accrued liabilities$4,653 $7,564 

In March 2025, the Company’s Board of Directors (the Board) took action to reduce the Company’s workforce by 57%. The Board also decided to exit the Company’s corporate headquarters in Warminster, Pennsylvania and to discontinue in-house scientific research. As a result, the Company recorded a one-time restructuring charge of $12.4 million in the first quarter of 2025, of which there was $0.5 million in severance and benefit costs and $0.3 million of lease-related operation expenses accrued as of September 30, 2025.