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Collaborations, contracts and licensing agreements (Tables)
9 Months Ended
Sep. 30, 2025
Revenue from Contract with Customer [Abstract]  
Summary of collaborations
Revenues are summarized in the following table:
Three Months Ended September 30,Nine Months Ended September 30,
2025202420252024
(in thousands)(in thousands)
Revenue from collaborations and licenses
Acuitas Therapeutics, Inc.$280 $644 $1,375 $1,981 
Qilu Pharmaceutical Co., Ltd.— 123 10,434 880 
Non-cash royalty revenue
Alnylam Pharmaceuticals, Inc.249 572 1,223 1,736 
Total revenue$529 $1,339 $13,032 $4,597