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Segment Reporting (Tables)

9 Months Ended

Sep. 30, 2025

Segment Reporting [Abstract]

Schedule of Segment Reporting Information, by Segment

			Three Months Ended September 30,												Nine Months Ended September 30,
			2025						2024						2025						2024
			(in thousands)
Revenue			$	529					$	1,339					$	13,032					$	4,597
Less:
Research and development employee expense, lab supplies and overhead			3,194						6,166						9,927						20,174
Imdusiran IM-PROVE I, II & III clinical trials expense			1,073						5,031						4,862						14,430
AB-101-001 Phase 1a/1b clinical trial expense			1,134						2,931						4,771						8,927
Other research and development programs expense			377						145						675						1,696
General and administrative expense			3,044						4,537						12,204						17,396
Restructuring expense			98						3,625						12,636						3,625
Other segment expense (1)			303						367						893						857
Add:
Interest income			952						1,746						3,191						5,120
Segment net loss			$	(7,742)					$	(19,717)					$	(29,745)					$	(57,388)
Adjustments and reconciling items			—						—						—						—
Consolidated net loss			$	(7,742)					$	(19,717)					$	(29,745)					$	(57,388)

(1) Other segment expense includes the change in the fair value of contingent consideration, non-cash interest expenses and foreign currency exchange gains and losses.

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- Definition

Tabular disclosure of the profit or loss and total assets for each reportable segment. An entity discloses certain information on each reportable segment if the amounts (a) are included in the measure of segment profit or loss reviewed by the chief operating decision maker or (b) are otherwise regularly provided to the chief operating decision maker, even if not included in that measure of segment profit or loss.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 25
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482810/280-10-50-25

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 22
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482810/280-10-50-22

Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 30
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482810/280-10-50-30

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X

- References

No definition available.

+ Details

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