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Restructuring (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended
Mar. 31, 2025
Sep. 30, 2025
Dec. 31, 2024
Restructuring Cost and Reserve [Line Items]      
Restructuring liabilities   $ (763) $ 0
Restructuring And Workforce Reduction      
Restructuring Cost and Reserve [Line Items]      
Restructuring and related cost, number of positions eliminated, percent 57.00%    
Impairment of leasehold improvements   1,900  
Impairment of laboratory equipment   900  
Operating Lease, Impairment Loss   900  
Restructuring And Workforce Reduction | Employee Severance      
Restructuring Cost and Reserve [Line Items]      
Cash severance   6,100  
Restructuring liabilities   (500)  
Restructuring And Workforce Reduction | Modification of Equity Awards      
Restructuring Cost and Reserve [Line Items]      
Noncash modification of equity awards   2,400  
Restructuring And Workforce Reduction | Accrual of lease-related operating expenses      
Restructuring Cost and Reserve [Line Items]      
Accrued lease-related operating expenses   (400)  
Restructuring liabilities   $ (300)