    <SEC-DOCUMENT>0001104659-21-126214-index.html : 20211014
    <SEC-HEADER>0001104659-21-126214.hdr.sgml : 20211014
    <ACCEPTANCE-DATETIME>20211014160251
    ACCESSION NUMBER:		0001104659-21-126214
    CONFORMED SUBMISSION TYPE:	424B5
    PUBLIC DOCUMENT COUNT:		6
    FILED AS OF DATE:		20211014
    DATE AS OF CHANGE:		20211014

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Rezolute, Inc.
    		CENTRAL INDEX KEY:			0001509261
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				273440894
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			0630

    	FILING VALUES:
    		FORM TYPE:		424B5
    		SEC ACT:		1933 Act
    		SEC FILE NUMBER:	333-251498
    		FILM NUMBER:		211323419

    	BUSINESS ADDRESS:
    		STREET 1:		201 REDWOOD SHORES PARKWAY, SUITE 315
    		CITY:			REDWOOD CITY
    		STATE:			CA
    		ZIP:			94065
    		BUSINESS PHONE:		650-847-1919

    	MAIL ADDRESS:
    		STREET 1:		201 REDWOOD SHORES PARKWAY, SUITE 315
    		CITY:			REDWOOD CITY
    		STATE:			CA
    		ZIP:			94065

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	AntriaBio, Inc.
    		DATE OF NAME CHANGE:	20130114

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	FITS MY STYLE INC
    		DATE OF NAME CHANGE:	20110104
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>424B5
    <SEQUENCE>1
    <FILENAME>tm2129111-4_424b5.htm
    <DESCRIPTION>424B5
    <TEXT>
    Document 1 - file: tm2129111-4_424b5.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>lg_rezolute-4clr.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 2 - file: lg_rezolute-4clr.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>tm2129111d1-fc_exist4clr.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 3 - file: tm2129111d1-fc_exist4clr.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>tm2129111d1-fc_circulat4clr.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 4 - file: tm2129111d1-fc_circulat4clr.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>tm2129111d1-lc_glucoseclr.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 5 - file: tm2129111d1-lc_glucoseclr.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>6
    <FILENAME>tm2129111d1-bc_vascu4clr.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 6 - file: tm2129111d1-bc_vascu4clr.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>