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SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Details 3) (USD $) | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2013 | Sep. 30, 2012 | Sep. 30, 2013 | Sep. 30, 2012
Stock-Based Compensation |  |  |  |
Stock-based compensation expense included in operating expenses | $ 1,222,000 | $ 1,263,000 | $ 3,456,000 | $ 4,016,000
Stock options | Certain members of executive management team |  |  |  |
Stock-Based Compensation |  |  |  |
Modifications to the Post-termination exercise period | 205,000 |  | 205,000 |
Research and development |  |  |  |
Stock-Based Compensation |  |  |  |
Stock-based compensation expense included in operating expenses | 483,000 | 594,000 | 1,394,000 | 1,861,000
Restructuring charges |  |  |  |
Stock-Based Compensation |  |  |  |
Stock-based compensation expense included in operating expenses |  |  | 28,000 |
General and administrative |  |  |  |
Stock-Based Compensation |  |  |  |
Stock-based compensation expense included in operating expenses | $ 739,000 | $ 669,000 | $ 2,034,000 | $ 2,155,000

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- Definition Represents the expense recognized during the period arising from equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments) with employees, directors and certain consultants qualifying for treatment as employees. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5047-113901 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB TOPIC 14.F) -URI http://asc.fasb.org/extlink&oid=27013229&loc=d3e301413-122809 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1)(i) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Staff Accounting Bulletin (SAB) -Number Topic 14 -Section F + Details
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- Definition An excess of the fair value of the modified award over the fair value of the award immediately before the modification. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(2)(iii) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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