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CONSOLIDATED STATEMENTS OF OPERATIONS (USD $) | 12 Months Ended
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Dec. 31, 2013 | Dec. 31, 2012 | Dec. 31, 2011
CONSOLIDATED STATEMENTS OF OPERATIONS |  |  |
Revenues from collaborative agreements |  |  | $ 300,000
License fees and royalties | 1,283,000 | 2,709,000 | 2,138,000
Total revenues | 1,283,000 | 2,709,000 | 2,438,000
Operating expenses: |  |  |
Research and development | 23,155,000 | 51,368,000 | 69,316,000
Restructuring charges | 1,462,000 | 2,702,000 | 5,449,000
General and administrative | 15,624,000 | 20,397,000 | 23,789,000
Total operating expenses | 40,241,000 | 74,467,000 | 98,554,000
Loss from operations | (38,958,000) | (71,758,000) | (96,116,000)
Unrealized (loss) gain on derivatives | (316,000) | 13,000 | 643,000
Interest and other income | 951,000 | 3,097,000 | 1,024,000
Losses recognized under equity method investment |  |  | (503,000)
Losses recognized from debt extinguishment |  |  | (1,664,000)
Interest and other expense | (56,000) | (233,000) | (237,000)
Net loss | $ (38,379,000) | $ (68,881,000) | $ (96,853,000)
Basic and diluted net loss per share (in dollars per share) | $ (0.30) | $ (0.54) | $ (0.78)
Shares used in computing basic and diluted net loss per share (in shares) | 128,380,800 | 126,941,024 | 124,506,763

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- Definition Revenue earned during the period relating to consideration received from another party for the right to use, but not own, certain of the entity's intangible assets. Licensing arrangements include, but are not limited to, rights to use a patent, copyright, technology, manufacturing process, software or trademark. Licensing fees are generally, but not always, fixed as to amount and not dependent upon the revenue generated by the licensing party. An entity may receive licensing fees for licenses that also generate royalty payments to the entity. Royalty revenue is derived from a percentage or stated amount of sales proceeds or revenue generated by the third party using the entity's property. Examples of property from which royalties may be derived include patents and oil and mineral rights. + References No definition available. + Details
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