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CONDENSED STATEMENTS OF CASH FLOWS CHANGE IN CASH AND CASH EQUIVALENTS (USD $) In Thousands, unless otherwise specified | 6 Months Ended
--- | ---
Jun. 30, 2014 | Jun. 30, 2013
Cash flows from operating activities: |  |
Net loss | $ (17,174) | $ (20,844)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation and amortization | 29 | 264
Accretion and amortization on investments, net | 1,456 | 647
Loss (gain) on retirement/sales of property and equipment, net | 3 | (116)
Loss on write-downs of property and equipment |  | 200
Stock-based compensation for services by non-employees | 149 | 53
Stock-based compensation for employees and directors | 3,743 | 2,234
Amortization related to 401(k) contributions | 76 | 465
Unrealized gain on derivatives | (77) | (1)
Changes in assets and liabilities: |  |
Other current and noncurrent assets | (419) | 1,248
Other current liabilities | (2,441) | (8,304)
Net cash used in operating activities | (14,655) | (24,154)
Cash flows from investing activities: |  |
Restricted cash transfer |  | (1)
Purchases of property and equipment |  | (56)
Proceeds from sales of property and equipment |  | 116
Purchases of marketable securities | (128,203) | (40,110)
Proceeds from maturities of marketable securities | 41,663 | 50,916
Net cash (used in) provided by investing activities | (86,540) | 10,865
Cash flows from financing activities: |  |
Proceeds from issuance of common stock, net of issuance costs | 97,725 | 60
Net cash provided by financing activities | 97,725 | 60
Net decrease in cash and cash equivalents | (3,470) | (13,229)
Cash and cash equivalents at the beginning of the period | 12,990 | 22,063
Cash and cash equivalents at the end of the period | $ 9,520 | $ 8,834

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- Definition Amount of currency on hand as well as demand deposits with banks or financial institutions. Includes other kinds of accounts that have the general characteristics of demand deposits. Also includes short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates. Excludes cash and cash equivalents within disposal group and discontinued operation. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Cash -URI http://asc.fasb.org/extlink&oid=6506951 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Cash Equivalents -URI http://asc.fasb.org/extlink&oid=6507016 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-X (SX) -Number 210 -Section 02 -Paragraph 1 -Article 5 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02.1) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 Reference 5: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section 45 -Paragraph 1 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=28358313&loc=d3e6676-107765 Reference 6: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 4 -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3044-108585 + Details
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- Definition Amount of cash inflow (outflow) from operating activities, excluding discontinued operations. Operating activity cash flows include transactions, adjustments, and changes in value not defined as investing or financing activities. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3602-108585 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 24 -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3521-108585 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 25 -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3536-108585 + Details
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