CONSOLIDATED STATEMENTS OF CASH FLOWS (USD $) In Thousands, unless otherwise specified	12 Months Ended
Dec. 31, 2014	Dec. 31, 2013	Dec. 31, 2012
Cash flows from operating activities:
Net loss	$ (35,670)us-gaap_NetIncomeLoss	$ (38,379)us-gaap_NetIncomeLoss	$ (68,881)us-gaap_NetIncomeLoss
Adjustments to reconcile net loss to net cash provided by (used in) operating activities:
Depreciation and amortization	47us-gaap_DepreciationNonproduction	320us-gaap_DepreciationNonproduction	830us-gaap_DepreciationNonproduction
Accretion and amortization on investments, net	2,889	1,322	2,184
Loss (gain) on retirement/sales of property and equipment, net	3	(831)	(142)
Loss on write-downs of property and equipment		200	271
Stock-based compensation for services by non-employees	253	252	183
Stock-based compensation for employees and directors	7,658us-gaap_ShareBasedCompensation	4,435us-gaap_ShareBasedCompensation	5,311us-gaap_ShareBasedCompensation
Amortization related to 401(k) contributions	111	458	726
Unrealized (gain) loss on derivatives	(351)us-gaap_UnrealizedGainLossOnDerivatives	316us-gaap_UnrealizedGainLossOnDerivatives	(13)us-gaap_UnrealizedGainLossOnDerivatives
Changes in assets and liabilities:
Interest and other receivables	(399)	188	646
Prepaid assets	(72)	1,081	1,311
Deposits and other assets	5	(4)	112
Accounts payable	(364)	(2,032)	449
Accrued compensation and benefits	580	(431)	3,548
Accrued restructuring charges	(94)	(1,878)	(1,758)
Accrued liabilities	(246)	(1,697)	(92)
Deferred revenue	35,000
Translation adjustment			169
Net cash provided by (used in) operating activities	9,350	(36,680)	(55,146)
Cash flows from investing activities:
Restricted cash transfer	529	(1)	(1)
Purchases of property and equipment	(131)	(3)	(862)
Proceeds from sales of property and equipment		1,196	170
Purchases of marketable securities	(190,263)	(88,977)	(79,369)
Proceeds from sales/calls of marketable securities	10,549
Proceeds from maturities of marketable securities	101,412	108,839	141,016
Net cash (used in) provided by investing activities	(77,904)	21,054	60,954
Cash flows from financing activities:
Proceeds from issuance of common stock, net of issuance costs	98,360	6,553	150
Net cash provided by financing activities	98,360	6,553	150
Net increase (decrease) in cash and cash equivalents	29,806	(9,073)	5,958
Cash and cash equivalents, at beginning of year	12,990	22,063	16,105
Cash and cash equivalents, at end of year	$ 42,796	$ 12,990	$ 22,063

The amount of noncash employee related expense charged against earnings during the reporting period for the vested portion of employer matching contributions in common stock under a defined-contribution savings plan under Section 401(k) of the Internal Revenue Code. As noncash, this element is an add back when calculating net cash generated by operating activities using the indirect method.

No definition available.