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STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($) $ in Thousands | Common Stock | Additional Paid-In Capital | Accumulated Deficit | Accumulated Other Comprehensive Income (Loss) | Total
--- | --- | --- | --- | --- | ---
Balances at Dec. 31, 2012 | $ 130 | $ 939,867 | $ (854,384) | $ 40 | $ 85,653
Balances (in shares) at Dec. 31, 2012 | 130,242,695 |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |
Net income (loss) |  |  | (38,379) |  | (38,379)
Other comprehensive loss |  |  |  | (54) | (54)
Stock-based compensation related to issuance of common stock and options in exchange for services |  | 252 |  |  | 252
Stock-based compensation related to issuance of common stock and options in exchange for services (in shares) | 66,853 |  |  |  |
Cancellations of non-vested restricted stock under equity plans, net of issuances of common stock |  | 6,553 |  |  | 6,553
Cancellations of non-vested restricted stock under equity plans, net of issuances of common stock (in shares) | (388,056) |  |  |  |
Stock-based compensation for equity-based awards to employees and directors |  | 4,435 |  |  | 4,435
401(k) contribution | $ 1 | 1,296 |  |  | 1,297
401(k) contribution (in shares) | 756,457 |  |  |  |
Balances at Dec. 31, 2013 | $ 131 | 952,403 | (892,763) | (14) | 59,757
Balances (in shares) at Dec. 31, 2013 | 130,677,949 |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |
Net income (loss) |  |  | (35,670) |  | (35,670)
Other comprehensive loss |  |  |  | (70) | (70)
Issuance of common stock in connection with public offering, net of issuance costs of $6,695,000 | $ 26 | 96,779 |  |  | 96,805
Issuance of common stock in connection with public offering, net of issuance costs (in shares) | 25,875,000 |  |  |  |
Stock-based compensation related to issuance of common stock and options in exchange for services |  | 253 |  |  | 253
Stock-based compensation related to issuance of common stock and options in exchange for services (in shares) | 71,239 |  |  |  |
Issuance of common stock upon net exercise of warrants (in shares) | 168,039 |  |  |  |
Issuances of common stock under equity plans, net of cancellations of non-vested restricted stock |  | 1,555 |  |  | 1,555
Issuances of common stock under equity plans, net of cancellations of non-vested restricted stock (in shares) | 564,950 |  |  |  |
Stock-based compensation for equity-based awards to employees and directors |  | 7,658 |  |  | 7,658
401(k) contribution |  | 424 |  |  | 424
401(k) contribution (in shares) | 72,694 |  |  |  |
Balances at Dec. 31, 2014 | $ 157 | 1,059,072 | (928,433) | (84) | $ 130,712
Balances (in shares) at Dec. 31, 2014 | 157,429,871 |  |  |  | 157,429,871
Increase (Decrease) in Stockholders' Equity |  |  |  |  |
Net income (loss) |  |  | 46 |  | $ 46
Other comprehensive loss |  |  |  | (129) | (129)
Stock-based compensation related to issuance of common stock and options in exchange for services |  | 364 |  |  | 364
Stock-based compensation related to issuance of common stock and options in exchange for services (in shares) | 18,077 |  |  |  |
Issuance of common stock upon exercise of warrants | $ 1 | 880 |  |  | 881
Issuance of common stock upon exercise of warrants (in shares) | 235,000 |  |  |  |
Issuances of common stock under equity plans, net of cancellations of non-vested restricted stock | $ 1 | 1,693 |  |  | 1,694
Issuances of common stock under equity plans, net of cancellations of non-vested restricted stock (in shares) | 1,098,411 |  |  |  |
Stock-based compensation for equity-based awards to employees and directors |  | 8,397 |  |  | 8,397
401(k) contribution |  | 161 |  |  | 161
Balances at Dec. 31, 2015 | $ 159 | $ 1,070,567 | $ (928,387) | $ (213) | $ 142,126
Balances (in shares) at Dec. 31, 2015 | 158,781,359 |  |  |  | 158,781,359

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