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CONDENSED STATEMENTS OF OPERATIONS - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Sep. 30, 2016
Sep. 30, 2015
Revenues:        
Collaboration revenue   $ 35,000,000   $ 35,000,000
License fees and royalties $ 5,108,000 363,000 $ 6,068,000 1,151,000
Total revenues 5,108,000 35,363,000 6,068,000 36,151,000
Operating expenses:        
Research and development 4,319,000 4,050,000 13,927,000 13,849,000
Restructuring charges   (41,000)   1,306,000
General and administrative 4,666,000 4,334,000 14,006,000 12,911,000
Total operating expenses 8,985,000 8,343,000 27,933,000 28,066,000
(Loss) income from operations (3,877,000) 27,020,000 (21,865,000) 8,085,000
Unrealized gain on derivatives       16,000
Interest and other income 322,000 187,000 871,000 481,000
Interest and other expense (21,000) (22,000) (61,000) (68,000)
Net (loss) income $ (3,576,000) $ 27,185,000 $ (21,055,000) $ 8,514,000
Net (loss) income per share:        
Basic (in dollars per share) $ (0.02) $ 0.17 $ (0.13) $ 0.05
Diluted (in dollars per share) $ (0.02) $ 0.17 $ (0.13) $ 0.05
Shares used in computing net (loss) income per share:        
Basic (in shares) 159,140,254 158,151,747 159,011,741 157,922,075
Diluted (in shares) 159,140,254 162,669,681 159,011,741 162,448,893