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STATEMENTS OF OPERATIONS - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2016 | Dec. 31, 2015 | Dec. 31, 2014
Revenues: |  |  |
Collaboration revenue |  | $ 35,000 |
License fees and royalties | $ 6,162 | 1,371 | $ 1,153
Total revenues | 6,162 | 36,371 | 1,153
Operating expenses: |  |  |
Research and development | 18,047 | 17,831 | 20,707
Restructuring charges |  | 1,306 |
General and administrative | 18,761 | 17,793 | 16,758
Total operating expenses | 36,808 | 36,930 | 37,465
Loss from operations | (30,646) | (559) | (36,312)
Unrealized gain on derivatives |  | 16 | 351
Interest and other income | 1,192 | 677 | 373
Interest and other expense | (83) | (88) | (82)
Net (loss) income | $ (29,537) | $ 46 | $ (35,670)
Net (loss) income per share: |  |  |
Basic (in dollars per share) | $ (0.19) | $ 0.00 | $ (0.23)
Diluted (in dollars per share) | $ (0.19) | $ 0.00 | $ (0.23)
Shares used in computing net (loss) income per share: |  |  |
Basic (in shares) | 159,045,644 | 158,036,162 | 153,540,341
Diluted (in shares) | 159,045,644 | 162,663,894 | 153,540,341

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- Definition Revenue earned during the period relating to consideration received from another party for the right to use, but not own, certain of the entity's intangible assets. Licensing arrangements include, but are not limited to, rights to use a patent, copyright, technology, manufacturing process, software or trademark. Licensing fees are generally, but not always, fixed as to amount and not dependent upon the revenue generated by the licensing party. An entity may receive licensing fees for licenses that also generate royalty payments to the entity. Royalty revenue is derived from a percentage or stated amount of sales proceeds or revenue generated by the third party using the entity's property. Examples of property from which royalties may be derived include patents and oil and mineral rights. + References No definition available. + Details
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