STATEMENTS OF OPERATIONS - USD ($) $ in Thousands	12 Months Ended
Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Revenues:
Collaboration revenue		$ 35,000
License fees and royalties	$ 6,162	1,371	$ 1,153
Total revenues	6,162	36,371	1,153
Operating expenses:
Research and development	18,047	17,831	20,707
Restructuring charges		1,306
General and administrative	18,761	17,793	16,758
Total operating expenses	36,808	36,930	37,465
Loss from operations	(30,646)	(559)	(36,312)
Unrealized gain on derivatives		16	351
Interest and other income	1,192	677	373
Interest and other expense	(83)	(88)	(82)
Net (loss) income	$ (29,537)	$ 46	$ (35,670)
Net (loss) income per share:
Basic (in dollars per share)	$ (0.19)	$ 0.00	$ (0.23)
Diluted (in dollars per share)	$ (0.19)	$ 0.00	$ (0.23)
Shares used in computing net (loss) income per share:
Basic (in shares)	159,045,644	158,036,162	153,540,341
Diluted (in shares)	159,045,644	162,663,894	153,540,341

Revenue earned during the period relating to consideration received from another party for the right to use, but not own, certain of the entity's intangible assets. Licensing arrangements include, but are not limited to, rights to use a patent, copyright, technology, manufacturing process, software or trademark. Licensing fees are generally, but not always, fixed as to amount and not dependent upon the revenue generated by the licensing party. An entity may receive licensing fees for licenses that also generate royalty payments to the entity. Royalty revenue is derived from a percentage or stated amount of sales proceeds or revenue generated by the third party using the entity's property. Examples of property from which royalties may be derived include patents and oil and mineral rights.

No definition available.