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STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($)
$ in Thousands
Common Stock
Additional Paid-In Capital
Accumulated Deficit
Accumulated Other Comprehensive Loss
Total
Balances at Dec. 31, 2013 $ 131 $ 952,403 $ (892,763) $ (14) $ 59,757
Balances (in shares) at Dec. 31, 2013 130,677,949        
Increase (Decrease) in Stockholders' Equity          
Net (loss) income     (35,670)   (35,670)
Other comprehensive (loss) income       (70) (70)
Issuance of common stock in connection with public offering, net of issuance costs of $6,695 $ 26 96,779     96,805
Issuance of common stock in connection with public offering, net of issuance costs (in shares) 25,875,000        
Stock-based compensation related to issuance of common stock and options in exchange for services   253     253
Stock-based compensation related to issuance of common stock and options in exchange for services (in shares) 71,239        
Issuance of common stock upon net exercise of warrants (in shares) 168,039        
Issuances of common stock under equity plans, net of cancellations of non-vested restricted stock   1,555     1,555
Issuances of common stock under equity plans, net of cancellations of non-vested restricted stock (in shares) 564,950        
Stock-based compensation for equity-based awards to employees and directors   7,658     7,658
401(k) contribution   424     424
401(k) contribution (in shares) 72,694        
Balances at Dec. 31, 2014 $ 157 1,059,072 (928,433) (84) 130,712
Balances (in shares) at Dec. 31, 2014 157,429,871        
Increase (Decrease) in Stockholders' Equity          
Net (loss) income     46   46
Other comprehensive (loss) income       (129) (129)
Stock-based compensation related to issuance of common stock and options in exchange for services   364     364
Stock-based compensation related to issuance of common stock and options in exchange for services (in shares) 18,077        
Issuance of common stock upon exercise of warrants $ 1 880     881
Issuance of common stock upon exercise of warrants (in shares) 235,000        
Issuances of common stock under equity plans, net of cancellations of non-vested restricted stock $ 1 1,693     1,694
Issuances of common stock under equity plans, net of cancellations of non-vested restricted stock (in shares) 1,098,411        
Stock-based compensation for equity-based awards to employees and directors   8,397     8,397
401(k) contribution   161     161
Balances at Dec. 31, 2015 $ 159 1,070,567 (928,387) (213) $ 142,126
Balances (in shares) at Dec. 31, 2015 158,781,359       158,781,359
Increase (Decrease) in Stockholders' Equity          
Net (loss) income     (29,537)   $ (29,537)
Other comprehensive (loss) income       160 160
Stock-based compensation related to issuance of common stock and options in exchange for services   156     156
Stock-based compensation related to issuance of common stock and options in exchange for services (in shares) 21,541        
Issuances of common stock under equity plans, net of cancellations of non-vested restricted stock   1,169     1,169
Issuances of common stock under equity plans, net of cancellations of non-vested restricted stock (in shares) 355,736        
Stock-based compensation for equity-based awards to employees and directors   8,245     8,245
401(k) contribution   61     61
Balances at Dec. 31, 2016 $ 159 $ 1,080,198 $ (957,924) $ (53) $ 122,380
Balances (in shares) at Dec. 31, 2016 159,158,636       159,158,636