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INCOME TAXES (Tables) | 12 Months Ended
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Dec. 31, 2017
Income Tax Disclosure [Abstract] |
Schedule of significant components of the entity's deferred tax assets | Deferred income taxes reflect the net tax effects of temporary differences between the carrying amounts of assets and liabilities for financial reporting purposes and the amounts used for income tax purposes. Significant components of our deferred tax assets are as follows:
|  | December 31, |
|  | 2017 |  |  | 2016 |
|  | (In thousands) |
Net operating loss carryforwards |  | $ | 187,700 |  |  | $ | 280,400 |
Research credits |  |  | 34,300 |  |  |  | 29,800 |
Capitalized research and development |  |  | 2,500 |  |  |  | 300 |
License fees |  |  | 100 |  |  |  | 200 |
Other-net |  |  | 8,200 |  |  |  | 11,500 |
Total deferred tax assets |  |  | 232,800 |  |  |  | 322,200 |
Valuation allowance for deferred tax assets |  |  | (232,800 | ) |  |  | (322,200 | )
Net deferred tax assets |  | $ | — |  |  | $ | — |
Schedule of reconciliation of the beginning and ending amounts of unrecognized tax benefits | A reconciliation of the beginning and ending amounts of unrecognized tax benefits is as follows (in thousands):
Balance as of December 31, 2016 |  | $ | 14,700 |
Increase related to current year tax positions |  |  | 1,200 |
Balance as of December 31, 2017 |  | $ | 15,900 |

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- Definition Tabular disclosure of the components of net deferred tax asset or liability recognized in an entity's statement of financial position, including the following: the total of all deferred tax liabilities, the total of all deferred tax assets, the total valuation allowance recognized for deferred tax assets. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=84230637&loc=d3e32537-109319 + Details
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- Definition Tabular disclosure of the change in unrecognized tax benefits. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 55 -Paragraph 217 -URI http://asc.fasb.org/extlink&oid=96868398&loc=d3e36027-109320 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 15A -URI http://asc.fasb.org/extlink&oid=84230637&loc=SL6600010-109319 + Details
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