STATEMENTS OF OPERATIONS - USD ($) $ in Thousands	12 Months Ended
Dec. 31, 2017	Dec. 31, 2016	Dec. 31, 2015
Revenues:
Collaboration revenue			$ 35,000
License fees and royalties	$ 1,065	$ 6,162	1,371
Total revenues	1,065	6,162	36,371
Operating expenses:
Research and development	11,033	18,047	17,831
Restructuring charges			1,306
General and administrative	19,287	18,761	17,793
Total operating expenses	30,320	36,808	36,930
Loss from operations	(29,255)	(30,646)	(559)
Unrealized gain on derivatives			16
Interest and other income	1,416	1,192	677
Interest and other expense	(77)	(83)	(88)
Net (loss) income	$ (27,916)	$ (29,537)	$ 46
Net (loss) income per share:
Basic	$ (0.18)	$ (0.19)	$ 0.00
Diluted	$ (0.18)	$ (0.19)	$ 0.00
Shares used in computing net (loss) income per share:
Basic	159,224,986	159,045,644	158,036,162
Diluted	159,224,986	159,045,644	162,663,894

Revenue earned during the period relating to consideration received from another party for the right to use, but not own, certain of the entity's intangible assets. Licensing arrangements include, but are not limited to, rights to use a patent, copyright, technology, manufacturing process, software or trademark. Licensing fees are generally, but not always, fixed as to amount and not dependent upon the revenue generated by the licensing party. An entity may receive licensing fees for licenses that also generate royalty payments to the entity. Royalty revenue is derived from a percentage or stated amount of sales proceeds or revenue generated by the third party using the entity's property. Examples of property from which royalties may be derived include patents and oil and mineral rights.

No definition available.