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STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($)
$ in Thousands
Total
Common Stock
Additional Paid-In Capital
Accumulated Deficit
Accumulated Other Comprehensive Loss
Balances at Dec. 31, 2014 $ 130,712 $ 157 $ 1,059,072 $ (928,433) $ (84)
Balances (in shares) at Dec. 31, 2014   157,429,871      
Increase (Decrease) in Stockholders' Equity          
Net (loss) income 46     46  
Other comprehensive (loss) income (129)       (129)
Stock-based compensation related to issuance of common stock and options in exchange for services 364   364    
Stock-based compensation related to issuance of common stock and options in exchange for services (in shares)   18,077      
Issuance of common stock upon exercise of warrants 881 $ 1 880    
Issuance of common stock upon exercise of warrants (in shares)   235,000      
Issuances of common stock under equity plans 1,694 $ 1 1,693    
Issuances of common stock under equity plans (in shares)   1,098,411      
Stock-based compensation for equity- based awards to employees and directors 8,397   8,397    
401(k) contribution 161   161    
Balances at Dec. 31, 2015 142,126 $ 159 1,070,567 (928,387) (213)
Balances (in shares) at Dec. 31, 2015   158,781,359      
Increase (Decrease) in Stockholders' Equity          
Net (loss) income (29,537)     (29,537)  
Other comprehensive (loss) income 160       160
Stock-based compensation related to issuance of common stock and options in exchange for services 156   156    
Stock-based compensation related to issuance of common stock and options in exchange for services (in shares)   21,541      
Issuances of common stock under equity plans 1,169   1,169    
Issuances of common stock under equity plans (in shares)   355,736      
Stock-based compensation for equity- based awards to employees and directors 8,245   8,245    
401(k) contribution 61   61    
Balances at Dec. 31, 2016 $ 122,380 $ 159 1,080,198 (957,924) (53)
Balances (in shares) at Dec. 31, 2016 159,158,636 159,158,636      
Increase (Decrease) in Stockholders' Equity          
Net (loss) income $ (27,916)     (27,916)  
Other comprehensive (loss) income (154)       (154)
Issuance of common stock in connection with at market offering, net of issuance costs of $114 1,060 $ 1 1,059    
Issuance of common stock in connection with at market offering, net of issuance costs (in shares)   614,230      
Stock-based compensation related to issuance of common stock and options in exchange for services 200   200    
Stock-based compensation related to issuance of common stock and options in exchange for services (in shares)   72,066      
Issuances of common stock under equity plans 51   51    
Issuances of common stock under equity plans (in shares)   32,307      
Stock-based compensation for equity- based awards to employees and directors 8,144   8,144    
401(k) contribution 32   32    
Balances at Dec. 31, 2017 $ 103,797 $ 160 $ 1,089,684 $ (985,840) $ (207)
Balances (in shares) at Dec. 31, 2017 159,877,239 159,877,239