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INCOME TAXES (Tables)
12 Months Ended
Dec. 31, 2018
Income Tax Disclosure [Abstract]  
Schedule of significant components of the entity's deferred tax assets

Deferred income taxes reflect the net tax effects of temporary differences between the carrying amounts of assets and liabilities for financial reporting purposes and the amounts used for income tax purposes. Significant components of our deferred tax assets are as follows:

 

 

 

December 31,

 

 

 

2018

 

 

2017

 

 

 

(In thousands)

 

Net operating loss carryforwards

 

$

192,100

 

 

$

187,700

 

Research credits

 

 

35,500

 

 

 

34,300

 

Capitalized research and development

 

 

2,500

 

 

 

2,500

 

License fees

 

 

 

 

 

100

 

Other-net

 

 

7,000

 

 

 

8,200

 

Total deferred tax assets

 

 

237,100

 

 

 

232,800

 

Valuation allowance for deferred tax assets

 

 

(237,100

)

 

 

(232,800

)

Net deferred tax assets

 

$

 

 

$

 

Schedule of reconciliation of the beginning and ending amounts of unrecognized tax benefits

A reconciliation of the beginning and ending amounts of unrecognized tax benefits is as follows (in thousands):

 

Balance as of December 31, 2017

 

$

15,900

 

Decrease related to prior year tax positions

 

 

(100

)

Increase related to current year tax positions

 

 

600

 

Balance as of December 31, 2018

 

$

16,400