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INCOME TAXES - DEFERRED TAXES (Details) - USD ($)	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2016
Significant components of deferred tax assets
Net operating loss carryforwards	$ 192,100,000	$ 187,700,000
Research credits	35,500,000	34,300,000
Capitalized research and development	2,500,000	2,500,000
License fees		100,000
Other-net	7,000,000	8,200,000
Total deferred tax assets	237,100,000	232,800,000
Valuation allowance for deferred tax assets	(237,100,000)	(232,800,000)
Valuation allowance
Increase (decrease) in valuation allowance	$ 4,300,000	$ (89,400,000)	$ 9,600,000

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