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CONDENSED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2019	Jun. 30, 2018
Cash flows from operating activities:
Net loss	$ (24,298)	$ (14,120)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	26	31
Accretion and amortization on investments, net	(958)	(111)
Change in fair value of equity investment, including foreign currency translation	3	513
Stock-based compensation for services by non-employees	33	120
Stock-based compensation for employees and directors	2,860	3,159
Amortization related to 401(k) contributions	9	10
Operating lease expense	334
Changes in assets and liabilities:
Current and noncurrent assets	(386)	146
Current liabilities	894	(1,611)
Net cash used in operating activities	(21,483)	(11,863)
Cash flows from investing activities:
Purchases of property and equipment	(67)
Purchases of marketable securities	(66,408)	(107,067)
Proceeds from maturities of marketable securities	94,851	37,850
Net cash provided by (used in) investing activities	28,376	(69,217)
Cash flows from financing activities:
Proceeds from issuances of common stock, net of issuance costs	243	83,873
Net cash provided by financing activities	243	83,873
Net increase in cash, cash equivalents and restricted cash	7,136	2,793
Cash, cash equivalents and restricted cash at the beginning of the period	10,844	16,603
Cash, cash equivalents and restricted cash at the end of the period	$ 17,980	$ 19,396

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