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STOCKHOLDERS' EQUITY - STOCK-BASED COMPENSATION EXPENSE FOR EMPLOYEES AND DIRECTORS (Details) - USD ($) $ in Thousands | 12 Months Ended
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Dec. 31, 2019 | Dec. 31, 2018 | Dec. 31, 2017
Stock-Based Compensation Expense |  |  |
Stock-based compensation expense included in operating expenses | $ 6,079 | $ 6,368 | $ 8,144
Research and development |  |  |
Stock-Based Compensation Expense |  |  |
Stock-based compensation expense included in operating expenses | 1,640 | 949 | 988
General and administrative |  |  |
Stock-Based Compensation Expense |  |  |
Stock-based compensation expense included in operating expenses | $ 4,439 | $ 5,419 | $ 7,156

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