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v3.20.1

STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2019 | Dec. 31, 2018 | Dec. 31, 2017
Cash flows from operating activities: |  |  |
Net loss | $ (68,548) | $ (27,017) | $ (27,916)
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |
Depreciation and amortization | 64 | 59 | 76
Loss on retirement/sales of property and equipment |  |  | 5
Accretion and amortization on investments, net | (1,534) | (978) | 273
Change in fair value of equity investment, including foreign currency translation | 196 | 604 |
Stock-based compensation for services by non-employees | 68 | 191 | 200
Stock-based compensation for employees and directors | 6,079 | 6,368 | 8,144
Amortization related to 401(k) contributions | 9 | 9 | 32
Amortization of right-of use-assets | 712 |  |
Changes in assets and liabilities: |  |  |
Interest and other receivables | 366 | (528) | 39
Prepaid assets | 121 | (752) | (56)
Deposit and other assets | (964) |  |
Accounts payable | 199 | 479 | 278
Accrued compensation and benefits | 2,188 | (743) | 542
Amount due to Janssen Biotech, Inc. | 11,659 | 908 | (1,665)
Accrued liabilities | 6,211 | 391 | (508)
Operating lease liabilities | (655) |  |
Net cash used in operating activities | (43,829) | (21,009) | (20,556)
Cash flows from investing activities: |  |  |
Purchases of property and equipment | (413) | (16) |
Purchases of marketable securities | (153,467) | (188,365) | (100,006)
Proceeds from maturities of marketable securities | 181,280 | 110,663 | 122,976
Net cash provided by (used in) investing activities | 27,400 | (77,718) | 22,970
Cash flows from financing activities: |  |  |
Proceeds from issuances of common stock under equity plans | 204 | 6,951 | 51
Proceeds from issuances of common stock from financings | 19,295 | 86,017 | 1,060
Net cash provided by financing activities | 19,499 | 92,968 | 1,111
Net increase (decrease) in cash, cash equivalents and restricted cash | 3,070 | (5,759) | 3,525
Cash, cash equivalents and restricted cash at the beginning of the period | 10,844 | 16,603 | 13,078
Cash, cash equivalents and restricted cash at the end of the period | $ 13,914 | $ 10,844 | $ 16,603

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