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CONDENSED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2020
Mar. 31, 2019
Cash flows from operating activities:    
Net loss $ (16,355) $ (10,059)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 27 15
Accretion and amortization on investments, net (124) (482)
Change in fair value of equity investment, including foreign currency translation 220 (103)
Stock-based compensation for services by non-employees 16 22
Stock-based compensation for employees and directors 1,568 1,426
Amortization related to 401(k) contributions   9
Amortization of right-of-use assets 244  
Changes in assets and liabilities:    
Current and noncurrent assets 249 (1,532)
Current and noncurrent liabilities (12,039) (2,034)
Net cash used in operating activities (26,194) (12,738)
Cash flows from investing activities:    
Purchases of property and equipment (191) (45)
Purchases of marketable securities (6,913) (44,092)
Proceeds from maturities of marketable securities 39,262 53,101
Net cash provided by investing activities 32,158 8,964
Cash flows from financing activities:    
Proceeds from issuances of common stock from financings 686  
Net cash provided by financing activities 686  
Net increase (decrease) in cash, cash equivalents and restricted cash 6,650 (3,774)
Cash, cash equivalents and restricted cash at the beginning of the period 13,914 10,844
Cash, cash equivalents and restricted cash at the end of the period $ 20,564 $ 7,070