<SEC-DOCUMENT>0001206774-20-001684.txt : 20200521
<SEC-HEADER>0001206774-20-001684.hdr.sgml : 20200521
<ACCEPTANCE-DATETIME>20200521215944
ACCESSION NUMBER:		0001206774-20-001684
CONFORMED SUBMISSION TYPE:	S-3MEF
PUBLIC DOCUMENT COUNT:		3
<REFERENCE-462B>333-225184
FILED AS OF DATE:		20200521
DATE AS OF CHANGE:		20200521
EFFECTIVENESS DATE:		20200521

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			GERON CORP
		CENTRAL INDEX KEY:			0000886744
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				752287752
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-3MEF
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-238595
		FILM NUMBER:		20903518

	BUSINESS ADDRESS:	
		STREET 1:		919 EAST HILLSDALE BOULEVARD
		STREET 2:		SUITE 250
		CITY:			FOSTER CITY
		STATE:			CA
		ZIP:			94404
		BUSINESS PHONE:		6504737700

	MAIL ADDRESS:	
		STREET 1:		919 EAST HILLSDALE BOULEVARD
		STREET 2:		SUITE 250
		CITY:			FOSTER CITY
		STATE:			CA
		ZIP:			94404

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	GERON CORPORATION
		DATE OF NAME CHANGE:	19960521
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-3MEF
<SEQUENCE>1
<FILENAME>geron3762711-s3mef.htm
<DESCRIPTION>A NEW REGISTRATION STATEMENT FILED UNDER RULE 462(B)
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<DIV style="TEXT-ALIGN: center"><B><FONT size=2 face="Times New Roman">As filed with the Securities and Exchange Commission on May </FONT></B><B><FONT size=2 face="Times New Roman">21</FONT></B><B><FONT size=2 face="Times New Roman">, 2020</FONT></B></DIV>
<DIV style="TEXT-ALIGN: right"><B><FONT size=2 face="Times New Roman">Registration No. 333-</FONT></B></DIV>
<DIV style="TEXT-ALIGN: right">
<DIV>
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<P style="TEXT-ALIGN: center"><B><FONT size=4 face="Times New Roman">UNITED STATES<BR></FONT></B><B><FONT size=4 face="Times New Roman">SECURITIES AND EXCHANGE COMMISSION<BR></FONT></B><B><FONT size=2 face="Times New Roman">WASHINGTON, D.C. 20549<BR>_____________________</FONT></B></P>
<div style="TEXT-ALIGN: center"><B><FONT size=4 face="Times New Roman">FORM S-3<BR>REGISTRATION STATEMENT<BR></FONT></B><B><I><FONT size=2 face="Times New Roman">UNDER<BR></FONT></I></B><B><I><FONT size=2 face="Times New Roman">THE SECURITIES ACT OF 1933<BR></FONT></I></B></div>
<div align=center>_____________________</div>
<P style="TEXT-ALIGN: center"><B><FONT size=6 face="Times New Roman">GERON CORPORATION<BR></FONT></B><B><FONT size=2 face="Times New Roman">(Exact name of Registrant as specified in its charter)</FONT></B></P>
<TABLE style="BORDER-COLLAPSE: COLLAPSE" cellSpacing=0 cellPadding=0 width="100%" border=0>

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   <TD width="50%" noWrap align=center><B><FONT size=2 face="Times New Roman">Delaware</FONT></B></TD>
   <TD width="49%" noWrap align=center><B><FONT size=2 face="Times New Roman">75-2287752</FONT></B></TD></TR>
<TR vAlign=bottom>
   <TD width="50%" noWrap align=center><B><FONT size=2 face="Times New Roman">(State or other jurisdiction of</FONT></B></TD>
   <TD width="49%" noWrap align=center><B><FONT size=2 face="Times New Roman">(I.R.S. Employer</FONT></B></TD></TR>
<TR vAlign=bottom>
   <TD width="50%" noWrap align=center><B><FONT size=2 face="Times New Roman">incorporation or organization)</FONT></B></TD>
   <TD width="49%" noWrap align=center><B><FONT size=2 face="Times New Roman">Identification Number)</FONT></B></TD></TR></TABLE>
 <div align=center>_____________________</div><BR>

<div style="TEXT-ALIGN: center"><B><FONT size=2 face="Times New Roman">919 E. Hillsdale Boulevard, Suite 250<BR>Foster City, California 94404<BR>(650) 473-7700<BR></FONT></B><B><FONT size=1 face="Times New Roman">(Address, including zip code, and telephone number, including area code, of Registrant&#8217;s principal executive offices)<BR></FONT></B></div>
<div align=center>_____________________</div>
<P style="TEXT-ALIGN: center"><B><FONT size=2 face="Times New Roman">John A. Scarlett<BR>President and Chief Executive Officer<BR>Geron Corporation<BR>919 E. Hillsdale Boulevard, Suite 250<BR>Foster City, California 94404<BR>(650) 473-7700</FONT></B></P>
<div style="TEXT-ALIGN: center"><B><FONT size=1 face="Times New Roman">(Name, address, including zip code, and telephone number, including area code, of agent for service)</FONT></B></div>
<div align=center>_____________________</div>
<P style="TEXT-ALIGN: center"><B><I><FONT size=2 face="Times New Roman">Copies to:</FONT></I></B></P>
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   <TD width="50%" noWrap align=center><B><FONT size=2 face="Times New Roman">Stephen N. Rosenfield</FONT></B></TD>
   <TD width="50%" noWrap align=center><B><FONT size=2 face="Times New Roman">Chadwick L. Mills</FONT></B></TD></TR>
<TR vAlign=bottom>
   <TD width="50%" noWrap align=center><B><FONT size=2 face="Times New Roman">Chief Legal Officer</FONT></B></TD>
   <TD width="50%" noWrap align=center><B><FONT size=2 face="Times New Roman">Cooley LLP</FONT></B></TD></TR>
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   <TD width="50%" noWrap align=center><B><FONT size=2 face="Times New Roman">Geron Corporation</FONT></B></TD>
   <TD width="50%" noWrap align=center><B><FONT size=2 face="Times New Roman">101 California Street</FONT></B></TD></TR>
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   <TD width="50%" noWrap align=center><B><FONT size=2 face="Times New Roman">919 E. Hillsdale Boulevard, Suite 250</FONT></B></TD>
   <TD width="50%" noWrap align=center><B><FONT size=2 face="Times New Roman">San Francisco, California 94111</FONT></B></TD></TR>
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   <TD width="50%" noWrap align=center><B><FONT size=2 face="Times New Roman">Foster City, California 94404</FONT></B></TD>
   <TD width="50%" noWrap align=center><B><FONT size=2 face="Times New Roman">(415) 693-2000</FONT></B></TD></TR>
<TR vAlign=bottom>
   <TD width="50%" noWrap align=center><B><FONT size=2 face="Times New Roman">(650) 473-7700</FONT></B></TD>
   <TD width="50%" noWrap align=left></TD></TR></TABLE>
<div align=center>_____________________</div>


<P STYLE="text-indent: 15pt; text-align: left"><B><FONT size=2 face="Times New Roman">Approximate date of commencement of proposed sale to the public: </FONT></B><FONT size=2 face="Times New Roman">As soon as practicable following the effectiveness of this registration statement.</FONT></P>
<P STYLE="text-indent: 15pt; text-align: left"><FONT size=2 face="Times New Roman">If the only securities being registered on this Form are being offered pursuant to dividend or interest reinvestment plans, please check the following box: &#9744;</FONT></P>
<P STYLE="text-indent: 15pt; text-align: left"><FONT size=2 face="Times New Roman">If any of the securities being registered on this Form are to be offered on a delayed or continuous basis pursuant to Rule 415 under the Securities Act of 1933, as amended, other than securities offered only in connection with dividend or interest reinvestment plans, check the following box: &#9746;</FONT></P>
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<P STYLE="text-indent: 15pt; text-align: left"><FONT size=2 face="Times New Roman">If this Form is filed to register additional securities for an offering pursuant to Rule 462(b) under the Securities Act, please check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering:</FONT><FONT size=2 face="Times New Roman">&nbsp;&#9746;&nbsp;</FONT><B><FONT size=2 face="Times New Roman">333-225184</FONT></B></P>
<P STYLE="text-indent: 15pt; text-align: left"><FONT size=2 face="Times New Roman">If this Form is a post-effective amendment filed pursuant to Rule 462(c) under the Securities Act, check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering. &#9744;</FONT></P>
<P STYLE="text-indent: 15pt; text-align: left"><FONT size=2 face="Times New Roman">If this Form is a registration statement pursuant to General Instruction I.D. or a post-effective amendment thereto that shall become effective upon filing with the Commission pursuant to Rule 462(e) under the Securities Act, check the following box. &#9744;</FONT></P>
<P STYLE="text-indent: 15pt; text-align: left"><FONT size=2 face="Times New Roman">If this Form is a post-effective amendment to a registration statement filed pursuant to General Instruction I.D. filed to register additional securities or additional classes of securities pursuant to Rule 413(b) under the Securities Act, check the following box. &#9744;</FONT></P>
<P STYLE="text-indent: 15pt; text-align: left"><FONT size=2 face="Times New Roman">Indicate by check mark whether the Registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company. See the definitions of &#8220;large accelerated filer,&#8221; &#8220;accelerated filer,&#8221; &#8220;smaller reporting company&#8221; and &#8220;emerging growth company&#8221; in Rule 12b-2 of the Exchange Act.</FONT></P>
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   <TD STYLE="width: 15%; white-space: nowrap; text-align: left"><FONT size=2 face="Times New Roman">Large accelerated filer&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</FONT></TD>
   <TD STYLE="width: 65%; white-space: nowrap; text-align: left"><FONT size=2 face="Times New Roman">&#9744;</FONT></TD>
   <TD STYLE="width: 15%; white-space: nowrap; text-align: left"><FONT size=2 face="Times New Roman">Accelerated filer</FONT></TD>
   <TD STYLE="width: 1%; white-space: nowrap; text-align: right"><FONT size=2 face="Times New Roman">&#9746;</FONT></TD></TR>
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   <TD STYLE="white-space: nowrap; text-align: left"><FONT size=2 face="Times New Roman">Non-accelerated filer</FONT></TD>
   <TD STYLE="white-space: nowrap; text-align: left"><FONT size=2 face="Times New Roman">&#9744;&nbsp;&nbsp;</FONT><FONT size=2 face="Times New Roman">(Do not check if a smaller reporting company)</FONT></TD>
   <TD STYLE="white-space: nowrap; text-align: left"><FONT size=2 face="Times New Roman">Smaller reporting company&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</FONT></TD>
   <TD STYLE="white-space: nowrap; text-align: right"><FONT size=2 face="Times New Roman">&#9746;</FONT></TD></TR>
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   <TD STYLE="white-space: nowrap; text-align: left"></TD>
   <TD STYLE="white-space: nowrap; text-align: left"></TD>
   <TD STYLE="white-space: nowrap; text-align: left"><FONT size=2 face="Times New Roman">Emerging growth company</FONT></TD>
   <TD STYLE="white-space: nowrap; text-align: right"><FONT size=2 face="Times New Roman">&#9744;</FONT></TD></TR></TABLE>
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<DIV STYLE="text-indent: 15pt; text-align: left"><FONT size=2 face="Times New Roman">If an emerging growth company, indicate by check mark if the Registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. &#9744;</FONT></div>
<div align=center>_____________________</div>
<P style="TEXT-ALIGN: center"><B><FONT size=2 face="Times New Roman">CALCULATION OF REGISTRATION FEE</FONT></B></P>
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   <TD STYLE="width: 96%; white-space: nowrap; text-align: left; border-top: Black 2pt double"></TD>
   <TD STYLE="width: 1%; white-space: nowrap; text-align: right; border-top: Black 2pt double">&nbsp;&nbsp;&nbsp; </TD>
   <TD STYLE="width: 1%; white-space: nowrap; text-align: center; border-top: Black 2pt double"><B><FONT size=2 face="Times New Roman">Proposed</FONT></B></TD>
   <TD STYLE="width: 1%; white-space: nowrap; text-align: center; border-top: Black 2pt double">&nbsp;&nbsp;&nbsp; </TD>
   <TD STYLE="width: 1%; white-space: nowrap; text-align: center; border-top: Black 2pt double"></TD></TR>
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   <TD width="96%" noWrap align=left></TD>
   <TD width="1%" noWrap align=right></TD>
   <TD width="1%" noWrap align=center><B><FONT size=2 face="Times New Roman">Maximum</FONT></B></TD>
   <TD width="1%" noWrap align=center></TD>
   <TD width="1%" noWrap align=center><B><FONT size=2 face="Times New Roman">Amount of</FONT></B></TD></TR>
<TR vAlign=bottom>
   <TD width="96%" noWrap align=center><B><FONT size=2 face="Times New Roman">Title of Each Class of</FONT></B></TD>
   <TD width="1%" noWrap align=right></TD>
   <TD width="1%" noWrap align=center><B><FONT size=2 face="Times New Roman">Aggregate</FONT></B></TD>
   <TD width="1%" noWrap align=center></TD>
   <TD width="1%" noWrap align=center><B><FONT size=2 face="Times New Roman">Registration</FONT></B></TD></TR>
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   <TD STYLE="width: 96%; white-space: nowrap; text-align: center; border-bottom: Black 1pt solid"><B><FONT size=2 face="Times New Roman">Securities to be Registered</FONT></B></TD>
   <TD width="1%" noWrap align=right></TD>
   <TD STYLE="width: 1%; white-space: nowrap; text-align: center; border-bottom: Black 1pt solid"><B><FONT size=2 face="Times New Roman">Offering Price(1)</FONT></B></TD>
   <TD width="1%" noWrap align=center></TD>
   <TD STYLE="width: 1%; white-space: nowrap; text-align: center; border-bottom: Black 1pt solid"><B><FONT size=2 face="Times New Roman">Fee(2)</FONT></B></TD></TR>
<TR STYLE="vertical-align: bottom; background-color: #cceeff">
   <TD width="96%" noWrap align=left><FONT size=2 face="Times New Roman">Common Stock, par value $0.001 per share</FONT></TD>
   <TD width="1%" noWrap align=right></TD>
   <TD width="1%" noWrap align=center><FONT size=2 face="Times New Roman">(1)</FONT></TD>
   <TD width="1%" noWrap align=center></TD>
   <TD width="1%" noWrap align=center><FONT size=2 face="Times New Roman">&#8212;</FONT></TD></TR>
<TR STYLE="vertical-align: bottom">
   <TD width="96%" noWrap align=left><FONT size=2 face="Times New Roman">Warrants to purchase shares of Common Stock, par value $0.001 per share</FONT></TD>
   <TD width="1%" noWrap align=right></TD>
   <TD width="1%" noWrap align=center><FONT size=2 face="Times New Roman">(1)</FONT></TD>
   <TD width="1%" noWrap align=center><FONT size=2 face="Times New Roman"></FONT></TD>
   <TD width="1%" noWrap align=center><FONT size=2 face="Times New Roman">&#8212;</FONT></TD></TR>
<TR STYLE="vertical-align: bottom; background-color: #cceeff">
   <TD STYLE="width: 96%; white-space: nowrap; text-align: left; border-bottom: Black 2pt double"><FONT size=2 face="Times New Roman">Total</FONT></TD>
   <TD STYLE="width: 1%; white-space: nowrap; text-align: right; border-bottom: Black 2pt double"></TD>
   <TD STYLE="width: 1%; white-space: nowrap; text-align: center; border-bottom: Black 2pt double"><FONT size=2 face="Times New Roman">$37,435,660</FONT></TD>
   <TD STYLE="width: 1%; white-space: nowrap; text-align: center; border-bottom: Black 2pt double"></TD>
   <TD STYLE="width: 1%; white-space: nowrap; text-align: center; border-bottom: Black 2pt double"><FONT size=2 face="Times New Roman"><FONT size=2 face="Times New Roman">$</FONT>4,859.15(3)</FONT></TD></TR></TABLE>
<B><FONT size=2 face="Times New Roman">_____________________</FONT></B><BR><BR>
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   <TD STYLE="vertical-align: top; width: 1%; white-space: nowrap; text-align: right; padding-right: 8pt"><FONT size=2 face="Times New Roman">(1)</FONT></TD>
   <TD width="99%" align=left><FONT size=2 face="Times New Roman">The Registrant previously registered the offer and sale of certain securities, including shares of its common stock, par value $0.001 per share (the &#8220;Common Stock&#8221;) and warrants having a proposed maximum aggregate offering price of $250,000,000 pursuant to a Registration Statement on Form S-3 (File No.333-225184), which was declared effective by the Securities and Exchange Commission on July 12, 2018 (the &#8220;Related Registration Statement&#8221;). As of the date hereof, a balance of $223,708,348 of such securities remains to be offered and sold under the Related Registration Statement. In accordance with Rule 462(b) promulgated under the Securities Act of 1933, as amended (the &#8220;Securities Act&#8221;) an additional amount of the Registrant&#8217;s Common Stock and warrants to purchase its Common Stock having a proposed maximum aggregate offering price of $37,435,660 is hereby registered, representing no more than 20% of the maximum aggregate offering price of unsold securities under the Related Registration.</FONT></TD></TR>
<TR STYLE="vertical-align: bottom">
   <TD STYLE="vertical-align: top; white-space: nowrap; text-align: right; padding-right: 8pt">&nbsp;</TD>
   <TD STYLE="text-align: left">&nbsp;</TD></TR>
<TR vAlign=bottom>
   <TD STYLE="vertical-align: top; width: 1%; white-space: nowrap; text-align: right; padding-right: 8pt"><FONT size=2 face="Times New Roman"></FONT></TD>
   <TD vAlign=top width="99%" noWrap align=left><FONT size=2 face="Times New Roman"></FONT></TD></TR>
<TR vAlign=bottom>
   <TD STYLE="vertical-align: top; width: 1%; white-space: nowrap; text-align: right; padding-right: 8pt"><FONT size=2 face="Times New Roman">(2)</FONT></TD>
   <TD vAlign=top width="99%" noWrap align=left><FONT size=2 face="Times New Roman">Calculated pursuant to Rule 457(o) under the Securities Act.</FONT></TD></TR>                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   <TR STYLE="vertical-align: bottom">
   <TD STYLE="vertical-align: top; white-space: nowrap; text-align: right; padding-right: 8pt">&nbsp;</TD>
   <TD STYLE="vertical-align: top; white-space: nowrap; text-align: left">&nbsp;</TD></TR>
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   <TD STYLE="vertical-align: top; width: 1%; white-space: nowrap; text-align: right; padding-right: 8pt"><FONT size=2 face="Times New Roman">(3)</FONT></TD>
   <TD vAlign=top width="99%" noWrap align=left><FONT size=2 face="Times New Roman">Previously paid.</FONT></TD></TR>
</TABLE>

<div align=center>_____________________</div>
<P STYLE="text-indent: 15pt; text-align: left"><B><FONT size=2 face="Times New Roman">This Registration Statement shall become effective upon filing in accordance with Rule 462(b) under the Securities Act of 1933, as amended.</FONT></B></P>
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<P style="TEXT-ALIGN: center"><B><FONT size=2 face="Times New Roman">EXPLANATORY NOTE AND INCORPORATION<BR>OF CERTAIN INFORMATION BY REFERENCE</FONT></B></P>
<P STYLE="text-indent: 15pt; text-align: left"><FONT size=2 face="Times New Roman">This Registration Statement is being filed pursuant to Rule 462(b) of the Securities Act of 1933, as amended (the "Securities Act"), and General Instruction IV(A) to Form S-3.  This Registration Statement relates to the public offering of securities contemplated by the Registration Statement on Form S-3 (File No. 333-225184) (the "Prior Registration Statement"), which the Registrant initially filed with the Securities and Exchange Commission on May 24, 2018, amended on July 10, 2018 and declared effective by the Securities and Exchange Commission on July 12, 2018.  </FONT></P>
<P STYLE="text-indent: 15pt; text-align: left"><FONT size=2 face="Times New Roman">The Registrant is filing this Registration Statement in order to replace in its entirety its prior Registration Statement on Form S-3 filed pursuant to Rule 462(b) under the Securities Act on May 21, 2020 (File No. 333-238592) (the "Prior S-3MEF") which included a scrivener's error in the footnotes to the Calculation of Registration Fee table included in the Prior S-3MEF.  </FONT></P>
<P STYLE="text-indent: 15pt; text-align: left"><FONT size=2 face="Times New Roman">In accordance with Rule 462(b), this Registration Statement incorporates by reference the contents of the Prior Registration Statement, including all exhibits thereto and all information incorporated by reference therein, other than the exhibits included herein.</FONT></P>
<P STYLE="text-indent: 15pt; text-align: left"><FONT size=2 face="Times New Roman">The required opinion and consents are listed on the Exhibit Index set forth below and filed herewith.</FONT></P>
<P style="TEXT-ALIGN: center"><B><FONT size=2 face="Times New Roman">EXHIBIT INDEX</FONT></B></P>
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   <TD width="1%" noWrap align=center><B><FONT size=2 face="Times New Roman">Exhibit</FONT></B></TD>
   <TD width="1%" noWrap align=center><B><FONT size=2 face="Times New Roman">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </FONT></B></TD>
   <TD STYLE="width: 82%; text-align: left"></TD>
   <TD width="1%" noWrap align=left><B><FONT size=2 face="Times New Roman">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </FONT></B></TD>
   <TD COLSPAN="7" STYLE="width: 15%; white-space: nowrap; text-align: center; border-bottom: Black 1pt solid"><B><FONT size=2 face="Times New Roman">Incorporation By Reference</FONT></B></TD></TR>
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   <TD STYLE="width: 1%; white-space: nowrap; text-align: center; border-bottom: Black 1pt solid"><B><FONT size=2 face="Times New Roman">Number</FONT></B></TD>
   <TD width="1%" noWrap align=center><B><FONT size=2 face="Times New Roman"></FONT></B></TD>
   <TD STYLE="border-bottom: Black 1pt solid; width: 82%; text-align: center"><B><FONT size=2 face="Times New Roman">Exhibit Description</FONT></B></TD>
   <TD width="1%" noWrap align=left></TD>
   <TD STYLE="width: 3%; white-space: nowrap; text-align: center; border-bottom: Black 1pt solid"><B><FONT size=2 face="Times New Roman">Form</FONT></B></TD>
   <TD width="1%" noWrap align=center><B><FONT size=2 face="Times New Roman"><B><FONT size=2 face="Times New Roman">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </FONT></B></FONT></B></TD>
   <TD STYLE="width: 3%; white-space: nowrap; text-align: center; border-bottom: Black 1pt solid"><B><FONT size=2 face="Times New Roman">SEC File No.</FONT></B></TD>
   <TD width="1%" noWrap align=center><B><FONT size=2 face="Times New Roman"><B><FONT size=2 face="Times New Roman">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </FONT></B></FONT></B></TD>
   <TD STYLE="width: 3%; white-space: nowrap; text-align: center; border-bottom: Black 1pt solid"><B><FONT size=2 face="Times New Roman">Exhibit</FONT></B></TD>
   <TD width="1%" noWrap align=center><B><FONT size=2 face="Times New Roman"><B><FONT size=2 face="Times New Roman">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </FONT></B></FONT></B></TD>
   <TD STYLE="width: 3%; white-space: nowrap; text-align: center; border-bottom: Black 1pt solid"><B><FONT size=2 face="Times New Roman">Filing Date</FONT></B></TD></TR>
<TR STYLE="vertical-align: bottom; background-color: #cceeff">
   <TD width="1%" noWrap align=center><A HREF="geron3762711-ex51.htm" STYLE="-sec-extract: exhibit"><FONT size=2 face="Times New Roman">5.1</FONT></A></TD>
   <TD width="1%" noWrap align=center><FONT size=2 face="Times New Roman"></FONT></TD>
   <TD STYLE="width: 82%; text-align: left"><A HREF="geron3762711-ex51.htm" STYLE="-sec-extract: exhibit"><FONT size=2 face="Times New Roman">Opinion of Cooley LLP</FONT></A></TD>
   <TD width="1%" noWrap align=left></TD>
   <TD width="3%" noWrap align=center><A HREF="geron3762711-ex51.htm" STYLE="-sec-extract: exhibit"><FONT size=2 face="Times New Roman">&#8212;</FONT></A></TD>
   <TD width="1%" noWrap align=center><FONT size=2 face="Times New Roman"></FONT></TD>
   <TD width="3%" noWrap align=center><A HREF="geron3762711-ex51.htm" STYLE="-sec-extract: exhibit"><FONT size=2 face="Times New Roman">&#8212;</FONT></A></TD>
   <TD width="1%" noWrap align=center><FONT size=2 face="Times New Roman"></FONT></TD>
   <TD width="3%" noWrap align=center><A HREF="geron3762711-ex51.htm" STYLE="-sec-extract: exhibit"><FONT size=2 face="Times New Roman">&#8212;</FONT></A></TD>
   <TD width="1%" noWrap align=center><FONT size=2 face="Times New Roman"></FONT></TD>
   <TD width="3%" noWrap align=center><A HREF="geron3762711-ex51.htm" STYLE="-sec-extract: exhibit"><FONT size=2 face="Times New Roman">&#8212;</FONT></A></TD></TR>
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   <TD WIDTH="1%" NOWRAP STYLE="text-align: center; vertical-align: top"><A HREF="geron3762711-ex231.htm" STYLE="-sec-extract: exhibit"><FONT size=2 face="Times New Roman">23.1</FONT></A></TD>
   <TD width="1%" noWrap align=center><FONT size=2 face="Times New Roman"></FONT></TD>
   <TD STYLE="width: 82%; text-align: left"><A HREF="geron3762711-ex231.htm" STYLE="-sec-extract: exhibit"><FONT size=2 face="Times New Roman">Consent of Independent Registered Public Accounting Firm</FONT></A></TD>
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   <TD width="3%" noWrap align=center><A HREF="geron3762711-ex231.htm" STYLE="-sec-extract: exhibit"><FONT size=2 face="Times New Roman">&#8212;</FONT></A></TD>
   <TD width="1%" noWrap align=center><FONT size=2 face="Times New Roman"></FONT></TD>
   <TD width="3%" noWrap align=center><A HREF="geron3762711-ex231.htm" STYLE="-sec-extract: exhibit"><FONT size=2 face="Times New Roman">&#8212;</FONT></A></TD>
   <TD width="1%" noWrap align=center><FONT size=2 face="Times New Roman"></FONT></TD>
   <TD width="3%" noWrap align=center><A HREF="geron3762711-ex231.htm" STYLE="-sec-extract: exhibit"><FONT size=2 face="Times New Roman">&#8212;</FONT></A></TD>
   <TD width="1%" noWrap align=center><FONT size=2 face="Times New Roman"></FONT></TD>
   <TD width="3%" noWrap align=center><A HREF="geron3762711-ex231.htm" STYLE="-sec-extract: exhibit"><FONT size=2 face="Times New Roman">&#8212;</FONT></A></TD></TR>
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   <TD width="1%" noWrap align=center><A HREF="geron3762711-ex51.htm" STYLE="-sec-extract: exhibit"><FONT size=2 face="Times New Roman">23.2</FONT></A></TD>
   <TD width="1%" noWrap align=center><FONT size=2 face="Times New Roman"></FONT></TD>
   <TD STYLE="width: 82%; text-align: left"><A HREF="geron3762711-ex51.htm" STYLE="-sec-extract: exhibit"><FONT size=2 face="Times New Roman">Consent of Cooley LLP (contained in Exhibit 5.1)</FONT></A></TD>
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   <TD width="3%" noWrap align=center><A HREF="geron3762711-ex51.htm" STYLE="-sec-extract: exhibit"><FONT size=2 face="Times New Roman">&#8212;</FONT></A></TD>
   <TD width="1%" noWrap align=center><FONT size=2 face="Times New Roman"></FONT></TD>
   <TD width="3%" noWrap align=center><A HREF="geron3762711-ex51.htm" STYLE="-sec-extract: exhibit"><FONT size=2 face="Times New Roman">&#8212;</FONT></A></TD>
   <TD width="1%" noWrap align=center><FONT size=2 face="Times New Roman"></FONT></TD>
   <TD width="3%" noWrap align=center><A HREF="geron3762711-ex51.htm" STYLE="-sec-extract: exhibit"><FONT size=2 face="Times New Roman">&#8212;</FONT></A></TD>
   <TD width="1%" noWrap align=center><FONT size=2 face="Times New Roman"></FONT></TD>
   <TD width="3%" noWrap align=center><A HREF="geron3762711-ex51.htm" STYLE="-sec-extract: exhibit"><FONT size=2 face="Times New Roman">&#8212;</FONT></A></TD></TR>
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   <TD width="1%" noWrap align=center><A HREF="http://www.sec.gov/Archives/edgar/data/886744/000135994818000004/geron33139014-s3.htm" STYLE="-sec-extract: exhibit"><FONT size=2 face="Times New Roman">24.1</FONT></A></TD>
   <TD width="1%" noWrap align=center><FONT size=2 face="Times New Roman"></FONT></TD>
   <TD STYLE="width: 82%; text-align: left"><A HREF="http://www.sec.gov/Archives/edgar/data/886744/000135994818000004/geron33139014-s3.htm" STYLE="-sec-extract: exhibit"><FONT size=2 face="Times New Roman">Power of Attorney (included on signature page)</FONT></A></TD>
   <TD width="1%" noWrap align=left></TD>
   <TD width="3%" noWrap align=center><A HREF="http://www.sec.gov/Archives/edgar/data/886744/000135994818000004/geron33139014-s3.htm" STYLE="-sec-extract: exhibit"><FONT size=2 face="Times New Roman">S-3</FONT></A></TD>
   <TD width="1%" noWrap align=center><FONT size=2 face="Times New Roman"></FONT></TD>
   <TD width="3%" noWrap align=center><A HREF="http://www.sec.gov/Archives/edgar/data/886744/000135994818000004/geron33139014-s3.htm" STYLE="-sec-extract: exhibit"><FONT size=2 face="Times New Roman">333-225184</FONT></A></TD>
   <TD width="1%" noWrap align=center><FONT size=2 face="Times New Roman"></FONT></TD>
   <TD width="3%" noWrap align=center><A HREF="http://www.sec.gov/Archives/edgar/data/886744/000135994818000004/geron33139014-s3.htm" STYLE="-sec-extract: exhibit"><FONT size=2 face="Times New Roman">24.1</FONT></A></TD>
   <TD width="1%" noWrap align=center><FONT size=2 face="Times New Roman"></FONT></TD>
   <TD width="3%" noWrap align=center><A HREF="http://www.sec.gov/Archives/edgar/data/886744/000135994818000004/geron33139014-s3.htm" STYLE="-sec-extract: exhibit"><FONT size=2 face="Times New Roman">May 24, 2018</FONT></A></TD></TR></TABLE>
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<DIV style="PAGE-BREAK-BEFORE: always"></DIV>


<P style="TEXT-ALIGN: center"><B><FONT size=2 face="Times New Roman">SIGNATURES</FONT></B></P>
<P STYLE="text-indent: 15pt; text-align: left"><FONT size=2 face="Times New Roman">Pursuant to the requirements of the Securities Act of 1933, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-3 and has duly caused this registration statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Foster City, State of California, on </FONT><FONT size=2 face="Times New Roman">May 21, 2020</FONT><FONT size=2 face="Times New Roman">.</FONT></P>
<TABLE style="LINE-HEIGHT: 14pt; BORDER-COLLAPSE: COLLAPSE" cellSpacing=0 cellPadding=0 width="100%" border=0>

<TR vAlign=bottom>
   <TD width="50%" noWrap align=left><B><FONT size=2 face="Times New Roman"></FONT></B></TD>
   <TD width="50%" colSpan=3 noWrap align=left><B><FONT size=2 face="Times New Roman"></FONT></B><B><FONT size=2 face="Times New Roman" style="font-variant: SMALL-CAPS">Geron Corporation</FONT></B></TD></TR>
<TR>
   <TD width="50%"></TD>
   <TD width="1%"></TD>
   <TD width="49%" colSpan=2>&nbsp;</TD></TR>
<TR vAlign=bottom>
   <TD width="50%" noWrap align=right><FONT size=2 face="Times New Roman"><FONT size=2 face="Times New Roman"></FONT></FONT></TD>
   <TD width="1%" noWrap align=right><FONT size=2 face="Times New Roman"><FONT size=2 face="Times New Roman">By:&nbsp; </FONT></FONT></TD>
   <TD style="BORDER-BOTTOM: #000000 1pt solid" width="25%" noWrap align=left><FONT size=2 face="Times New Roman">/s/ </font><FONT size=2 face="Times New Roman" style="font-variant: SMALL-CAPS">Stephen N. Rosenfield</FONT></TD>
   <TD width="24%" noWrap align=left>&nbsp;</TD></TR>
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   <TD width="50%" noWrap align=left><FONT size=2 face="Times New Roman"></FONT></TD>
   <TD width="1%" noWrap align=left><FONT size=2 face="Times New Roman"></FONT></TD>
   <TD width="49%" colSpan=2 noWrap align=left><FONT size=2 face="Times New Roman">Stephen N. Rosenfield</FONT></TD></TR>
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   <TD width="50%" noWrap align=left><FONT size=2 face="Times New Roman"></FONT></TD>
   <TD width="1%" noWrap align=left><FONT size=2 face="Times New Roman"></FONT></TD>
   <TD width="49%" colSpan=2 noWrap align=left><FONT size=2 face="Times New Roman">Executive Vice President, Chief</FONT></TD></TR>
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   <TD width="50%" align=left><FONT size=2 face="Times New Roman"></FONT></TD>
   <TD width="1%" align=left><FONT size=2 face="Times New Roman"></FONT></TD>
   <TD width="49%" colSpan=2 align=left><FONT size=2 face="Times New Roman">Legal Officer and Corporate</FONT></TD></TR>
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   <TD width="50%" noWrap align=left><FONT size=2 face="Times New Roman"></FONT></TD>
   <TD width="1%" noWrap align=left><FONT size=2 face="Times New Roman"></FONT></TD>
   <TD width="49%" colSpan=2 noWrap align=left><FONT size=2 face="Times New Roman">Secretary</FONT></TD></TR></TABLE>

<P STYLE="text-indent: 15pt; text-align: left"><FONT size=2 face="Times New Roman">Pursuant to the requirements of the Securities Act of 1933, this registration statement has been signed below by the following persons in the capacities and on the dates indicated.</FONT></P>
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<TR vAlign=bottom>
   <TD STYLE="border-bottom: Black 1pt solid; width: 33%; white-space: nowrap; text-align: center"><B><FONT size=2 face="Times New Roman">Signatures</FONT></B></TD>
    <TD STYLE="width: 1%">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</TD>
   <TD STYLE="border-bottom: Black 1pt solid; width: 32%; white-space: nowrap; text-align: center"><B><FONT size=2 face="Times New Roman">Title</FONT></B></TD>
    <TD STYLE="width: 1%">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</TD>
   <TD STYLE="border-bottom: Black 1pt solid; width: 33%; white-space: nowrap; text-align: center"><B><FONT size=2 face="Times New Roman">Date</FONT></B></TD></TR>
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   <TD STYLE="border-bottom: Black 1pt solid; white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman" >/s/ </font><FONT size=2 face="Times New Roman" style="font-variant: SMALL-CAPS">John A. Scarlett</FONT></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman">President, Chief Executive Officer and</FONT></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman">May 21, 2020</FONT></TD></TR>
<TR vAlign=bottom>
   <TD STYLE="white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman">John A. Scarlett</FONT></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman">Chairman of the Board</FONT></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: left"></TD></TR>
<TR vAlign=bottom>
   <TD STYLE="white-space: nowrap; text-align: left"></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: center"><I><FONT size=2 face="Times New Roman">(Principal Executive Officer)</FONT></I></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: left"></TD></TR>
<TR>
   <TD COLSPAN="5">&nbsp;</TD></TR>
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   <TD STYLE="border-bottom: Black 1pt solid; white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman">/s/ </font><FONT size=2 face="Times New Roman" style="font-variant: SMALL-CAPS">Olivia  Bloom</FONT></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman">Executive Vice President, Finance, Chief</FONT></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman">May 21, 2020</FONT></TD></TR>
<TR vAlign=bottom>
   <TD STYLE="white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman">Olivia K. Bloom</FONT></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman">Financial Officer and Treasurer</FONT></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: left"></TD></TR>
<TR vAlign=bottom>
   <TD STYLE="white-space: nowrap; text-align: center">&nbsp;</TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: center"><I><FONT size=2 face="Times New Roman">(Principal Financial and Accounting</FONT></I></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: left"></TD></TR>
<TR vAlign=bottom>
   <TD STYLE="white-space: nowrap; text-align: left"></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: center"><I><FONT size=2 face="Times New Roman">Officer)</FONT></I></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: left"></TD></TR>
<TR>
   <TD COLSPAN="5">&nbsp;</TD></TR>
<TR vAlign=bottom>
   <TD STYLE="border-bottom: Black 1pt solid; white-space: nowrap; text-align: center">&nbsp;</TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman">Director</FONT></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman">May 21, 2020</FONT></TD></TR>
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   <TD STYLE="white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman">Dawn C. Bir</FONT></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: left"></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: left"></TD></TR>
<TR>
   <TD COLSPAN="5">&nbsp;</TD></TR>
<TR vAlign=bottom>
   <TD STYLE="border-bottom: Black 1pt solid; white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman">*</FONT></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman">Director</FONT></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman">May 21, 2020</FONT></TD></TR>
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   <TD STYLE="white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman">Karin Eastham</FONT></TD>
    <TD>&nbsp;</TD>

   <TD STYLE="white-space: nowrap; text-align: left"></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: left"></TD></TR>
<TR>
   <TD COLSPAN="5">&nbsp;</TD></TR>
<TR vAlign=bottom>
   <TD STYLE="border-bottom: Black 1pt solid; white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman">*</FONT></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman">Director</FONT></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman">May 21, 2020</FONT></TD></TR>
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   <TD STYLE="white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman">V. Bryan Lawlis
</FONT></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: left"></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: left"></TD></TR>
<TR>
   <TD COLSPAN="5">&nbsp;</TD></TR>
<TR vAlign=bottom>
   <TD STYLE="border-bottom: Black 1pt solid; white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman">*</FONT></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman">Director</FONT></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman">May 21, 2020</FONT></TD></TR>
<TR vAlign=bottom>
   <TD STYLE="white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman">Susan M. Molineaux
</FONT></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: left"></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: left"></TD></TR>
<TR>
   <TD COLSPAN="5">&nbsp;</TD></TR>
<TR vAlign=bottom>
   <TD STYLE="border-bottom: Black 1pt solid; white-space: nowrap; text-align: center">&nbsp;</TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman">Director</FONT></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman">May 21, 2020</FONT></TD></TR>
<TR vAlign=bottom>
   <TD STYLE="white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman">Elizabeth O&#8217;Farrell</FONT></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: left"></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: left"></TD></TR>
<TR>
   <TD COLSPAN="5">&nbsp;</TD></TR>
<TR vAlign=bottom>
   <TD STYLE="border-bottom: Black 1pt solid; white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman">*</FONT></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman">Director</FONT></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman">May 21, 2020</FONT></TD></TR>
<TR vAlign=bottom>
   <TD STYLE="white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman">Robert J. Spiegel</FONT></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: left"></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: left"></TD></TR>                                                               <TR STYLE="vertical-align: bottom">
   <TD STYLE="white-space: nowrap; text-align: center">&nbsp;</TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: left">&nbsp;</TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: left">&nbsp;</TD></TR>

<TR vAlign=bottom>
   <TD STYLE="white-space: nowrap; text-align: center; width: 32%"><FONT size=2 face="Times New Roman">*By: </font><U><FONT size=2 face="Times New Roman">/s/ </FONT><FONT size=2 face="Times New Roman" style="font-variant: SMALL-CAPS">Olivia  Bloom</FONT></U></TD>
    <TD STYLE="width: 1%">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: center; width: 33%">&nbsp;</TD>
    <TD STYLE="width: 1%">&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: center; width: 33%"><FONT size=2 face="Times New Roman">May 21, 2020</FONT></TD></TR>
<TR vAlign=bottom>
   <TD STYLE="white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman">Olivia K. Bloom</FONT></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: center">&nbsp;</TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: left">&nbsp;</TD></TR>
<TR vAlign=bottom>
   <TD STYLE="white-space: nowrap; text-align: center"><FONT size=2 face="Times New Roman"><I>Attorney-in-Fact</I></FONT></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: center">&nbsp;</TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: left">&nbsp;</TD></TR>
<TR vAlign=bottom>
   <TD STYLE="white-space: nowrap; text-align: left"></TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: center">&nbsp;</TD>
    <TD>&nbsp;</TD>
   <TD STYLE="white-space: nowrap; text-align: left">&nbsp;</TD></TR>
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<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>2
<FILENAME>geron3762711-ex51.htm
<DESCRIPTION>OPINION OF COOLEY LLP
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<P style="TEXT-ALIGN: right"><B><FONT size=2 face="Times New Roman">Exhibit 5.1</FONT></B></P>
<P style="TEXT-ALIGN: center"><FONT size=2 face="Times New Roman">[Cooley Letterhead]</FONT></P>
<P style="TEXT-ALIGN: justify"><FONT size=2 face="Times New Roman">May 21, 2020</FONT></P>
<P style="TEXT-ALIGN: justify"><FONT size=2 face="Times New Roman">Geron Corporation<BR>919 East Hillsdale Boulevard, Suite 250<BR>Foster City, CA 94404</FONT></P>
<P style="TEXT-ALIGN: justify"><FONT size=2 face="Times New Roman">Ladies and Gentlemen:</FONT></P>
<P style="TEXT-ALIGN: justify"><FONT size=2 face="Times New Roman">We have acted as counsel to Geron Corporation, a Delaware corporation (the &#8220;</FONT><B><I><FONT size=2 face="Times New Roman">Company</FONT></I></B><FONT size=2 face="Times New Roman">&#8221;), in connection with the Registration Statement on Form S-3 (the &#8220;</FONT><B><I><FONT size=2 face="Times New Roman">Registration Statement</FONT></I></B><FONT size=2 face="Times New Roman">&#8221;) filed by the Company pursuant to Rule 462(b) promulgated under the Securities Act of 1933, as amended (the &#8220;</FONT><B><I><FONT size=2 face="Times New Roman">Act</FONT></I></B><FONT size=2 face="Times New Roman">&#8221;), relating to an aggregate of $37,435,660 of shares of common stock, par value $0.001 per share (the &#8220;</FONT><B><I><FONT size=2 face="Times New Roman">Common Stock</FONT></I></B><FONT size=2 face="Times New Roman">&#8221;), of the Company (the &#8220;</FONT><B><I><FONT size=2 face="Times New Roman">Shares</FONT></I></B><FONT size=2 face="Times New Roman">&#8221;) and warrants to purchase Common Stock (the &#8220;</FONT><B><I><FONT size=2 face="Times New Roman">Warrants</FONT></I></B><FONT size=2 face="Times New Roman">&#8221;), which may be issued under one or more warrant agreements, to be dated on or about the date of the first issuance of the Warrants thereunder, by and between a warrant agent to be selected by the Company (the &#8220;</FONT><B><I><FONT size=2 face="Times New Roman">Warrant Agent</FONT></I></B><FONT size=2 face="Times New Roman">&#8221;) and the Company, in the form filed as an exhibit to the Prior Registration Statement (as defined below) (the &#8220;</FONT><B><I><FONT size=2 face="Times New Roman">Warrant Agreement</FONT></I></B><FONT size=2 face="Times New Roman">&#8221;). The Registration Statement incorporates by reference the registration statement on Form S-3 (File No.333-225184), which was declared effective on July 12, 2018 (the &#8220;</FONT><B><I><FONT size=2 face="Times New Roman">Prior Registration Statement</FONT></I></B><FONT size=2 face="Times New Roman">&#8221;), including the prospectus which forms a part of the Prior Registration Statement (the &#8220;</FONT><B><I><FONT size=2 face="Times New Roman">Base Prospectus</FONT></I></B><FONT size=2 face="Times New Roman">&#8221;), which provides that it will be supplemented in the future by one or more prospectus supplements (each a &#8220;</FONT><B><I><FONT size=2 face="Times New Roman">Prospectus Supplement</FONT></I></B><FONT size=2 face="Times New Roman">&#8221;).</FONT></P>
<P style="TEXT-ALIGN: justify"><FONT size=2 face="Times New Roman">The Common Stock and the Warrants are collectively referred to as the &#8220;</FONT><B><I><FONT size=2 face="Times New Roman">Securities</FONT></I></B><FONT size=2 face="Times New Roman">&#8221;. The Securities are being registered for offer and sale from time to time pursuant to Rule 415 under the Securities Act. In connection with this opinion, we have examined and relied upon originals, or copies certified to our satisfaction, of such records, documents, certificates, opinions, memoranda and other instruments as in our judgment are necessary or appropriate to enable us to render the opinion expressed below. As to certain factual matters, we have relied upon a certificate of an officer of the Company and have not independently verified such matters.</FONT></P>
<P style="TEXT-ALIGN: justify"><FONT size=2 face="Times New Roman">In rendering this opinion, we have assumed the genuineness of all signatures, the authenticity of all documents submitted to us as originals, the conformity to originals of all documents submitted to us as copies; the accuracy, completeness and authenticity of certificates of public officials, and the due authorization, execution and delivery of all documents by all persons other than the Company where authorization, execution and delivery are prerequisites to the effectiveness of such documents.</FONT></P>
<P style="TEXT-ALIGN: justify"><FONT size=2 face="Times New Roman">With respect to our opinion as to the Common Stock, we have assumed that, at the time of issuance and sale, a sufficient number of shares of Common Stock is authorized and reserved or available for issuance and that the consideration for the issuance and sale of the Shares is in an amount that is not less than the par value of the Common Stock.</FONT></P>
<P style="TEXT-ALIGN: justify"><FONT size=2 face="Times New Roman">With respect to our opinion as to the Warrants, we have also assumed that any Warrants offered under the Registration Statement, and the related Warrant Agreement are executed in the forms filed as exhibits to the Registration Statement or incorporated by reference therein. We have also assumed that (i) with respect to Common Stock issuable upon exercise of any Warrants, such Warrants constitute valid and legally binding obligations of the Company, enforceable against the Company in accordance with their terms, except as enforcement may be limited by applicable bankruptcy, insolvency, reorganization, arrangement, moratorium or other similar laws affecting creditors&#8217; rights, and subject to general equity principles and to limitations on availability of equitable relief, including specific performance.</FONT></P>
<P style="TEXT-ALIGN: center"><FONT size=1 face="Times New Roman">Cooley LLP 101 California Street, 5<SUP>th </SUP>floor, CA 94111-5800<BR>t: (415) 693-2000 f: (415) 693-2222 cooley.com</FONT></P>
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<P style="TEXT-ALIGN: justify"><FONT size=2 face="Times New Roman">Geron Corporation<BR>May 21, 2020<BR>Page Two</FONT></P>
<P style="TEXT-ALIGN: justify"><FONT size=2 face="Times New Roman">Our opinion herein is expressed solely with respect to the General Corporation Law of the State of Delaware, and, as to the Warrants constituting valid and legally binding obligations of the Company, the laws of the State of New York. We express no opinion to the extent that any other laws are applicable to the subject matter hereof and express no opinion and provide no assurance as to compliance with any federal or state securities law, rule or regulation.</FONT></P>
<P style="TEXT-ALIGN: justify"><FONT size=2 face="Times New Roman">On the basis of the foregoing and in reliance thereon, and subject to the qualifications herein stated, we are of the opinion that:</FONT></P>
<P style="TEXT-ALIGN: justify"><FONT size=2 face="Times New Roman">1. With respect to the Common Stock offered under the Registration Statement, provided that (i) the Base Prospectus and any and all Prospectus Supplement(s) required by applicable laws have been delivered and filed as required by such laws; (ii) the issuance of the Common Stock has been duly authorized by all necessary corporate action on the part of the Company; (iii) the issuance and sale of the Common Stock do not violate any applicable law, are in conformity with the Company&#8217;s then operative certificate of incorporation (the &#8220;</FONT><B><I><FONT size=2 face="Times New Roman">Certificate of Incorporation</FONT></I></B><FONT size=2 face="Times New Roman">&#8221;) and bylaws (the &#8220;</FONT><B><I><FONT size=2 face="Times New Roman">Bylaws</FONT></I></B><FONT size=2 face="Times New Roman">&#8221;), do not result in a default under or breach of any agreement or instrument binding upon the Company and comply with any applicable requirement or restriction imposed by any court or governmental body having jurisdiction over the Company; and (iv) the certificates, if any, for the Common Stock have been duly executed by the Company, countersigned by the transfer agent therefor and duly delivered to the purchasers thereof against payment therefor, then the Common Stock, when issued and sold as contemplated in the Registration Statement, the Base Prospectus and the related Prospectus Supplement(s), and in accordance with a duly authorized, executed and delivered purchase, underwriting or similar agreement, or upon exercise of any Warrants in accordance with their terms, will be validly issued, fully paid and non-assessable.</FONT></P>
<P style="TEXT-ALIGN: justify"><FONT size=2 face="Times New Roman">2. With respect to the Warrants issued under the Warrant Agreement and offered under the Registration Statement, provided that (i) any and all Prospectus Supplement(s) required by applicable laws have been delivered and filed as required by such laws; (ii) the Warrant Agreement has been duly authorized by the Company and the Warrant Agent by all necessary corporate action; (iii) the Warrant Agreement has been duly executed and delivered by the Company and the Warrant Agent; (iv) the issuance and terms of the Warrants have been duly authorized by the Company by all necessary corporate action; (v) the terms of the Warrants and of their issuance and sale have been duly established in conformity with the Warrant Agreement and as described in the Registration Statement, the Base Prospectus and the related Prospectus Supplement(s), so as not to violate any applicable law or result in a default under or breach of any agreement or instrument binding upon the Company, so as to be in conformity with the Certificate of Incorporation and Bylaws, and so as to comply with any requirement or restriction imposed by any court or governmental body having jurisdiction over the Company; and (vi) the Warrants have been duly executed and delivered by the Company and authenticated by the Warrant Agent pursuant to the Warrant Agreement and delivered against payment therefor, then the Warrants, when issued and sold as contemplated in the Registration Statement, the Base Prospectus and the Prospectus Supplement(s) and in accordance with the Warrant Agreement and a duly authorized, executed and delivered purchase, underwriting or similar agreement, will be valid and legally binding obligations of the Company, enforceable against the Company in accordance with their terms, except as enforcement thereof may be limited by bankruptcy, insolvency, reorganization, moratorium or other similar laws relating to or affecting creditors&#8217; rights generally, and by general equitable principles (regardless of whether such enforceability is considered in a proceeding at law or in equity).</FONT></P>
<P style="TEXT-ALIGN: justify"><FONT size=2 face="Times New Roman">We hereby consent to the filing of this opinion as an exhibit to the Registration Statement and to reference to our firm under the caption &#8220;Legal Matters&#8221; in the Base Prospectus.</FONT></P>
<P style="TEXT-ALIGN: center"><FONT size=1 face="Times New Roman">Cooley LLP 101 California Street, 5<SUP>th </SUP>floor, CA 94111-5800<BR>t: (415) 693-2000 f: (415) 693-2222 cooley.com</FONT></P>
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<P style="TEXT-ALIGN: justify"><FONT size=2 face="Times New Roman">Geron Corporation<BR>May 21, 2020<BR>Page Three</FONT></P>
<P style="TEXT-ALIGN: justify"><FONT size=2 face="Times New Roman">Our opinion set forth above is limited to the matters expressly set forth in this letter, and no opinion is implied or may be inferred beyond the matters expressly stated. This opinion speaks only as to law and facts in effect or existing as of the date hereof, and we undertake no obligation or responsibility to update or supplement this opinion to reflect any facts or circumstances that may hereafter come to our attention or any changes in law that may hereafter occur.</FONT></P>
<P style="TEXT-ALIGN: justify"><FONT size=2 face="Times New Roman">Sincerely,</FONT></P>
<P style="TEXT-ALIGN: justify"><B><FONT style="FONT-VARIANT: small-caps" size=2 face="Times New Roman">Cooley LLP</FONT></B></P>
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   <TD width="1%" noWrap align=left><FONT size=2 face="Times New Roman">By:&nbsp;</FONT></TD>
   <TD style="BORDER-BOTTOM: #000000 1pt solid" width="99%" noWrap align=left><FONT size=2 face="Times New Roman">&nbsp;&nbsp;/s/ Chadwick Mills</FONT></TD></TR>
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   <TD width="1%" noWrap align=left></TD>
   <TD width="99%" noWrap align=left><FONT size=2 face="Times New Roman">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;C</FONT><FONT size=2 face="Times New Roman">HADWICK </FONT><FONT size=2 face="Times New Roman">L. M</FONT><FONT size=2 face="Times New Roman">ILLS</FONT></TD></TR></TABLE>

<P style="TEXT-ALIGN: center"><FONT size=1 face="Times New Roman">Cooley LLP 101 California Street, 5<SUP>th </SUP>floor, CA 94111-5800<BR>t: (415) 693-2000 f: (415) 693-2222 cooley.com</FONT></P>
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<TYPE>EX-23.1
<SEQUENCE>3
<FILENAME>geron3762711-ex231.htm
<DESCRIPTION>CONSENT OF ERNST & YOUNG LLP, INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
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<P style="TEXT-ALIGN: right"><B><FONT size=2 face="Times New Roman">EXHIBIT 23.1</FONT></B></P>
<P style="TEXT-ALIGN: center"><B><FONT size=2 face="Times New Roman">Consent of Independent Registered Public Accounting Firm</FONT></B></P>
<P style="TEXT-ALIGN: left"><FONT size=2 face="Times New Roman">We consent to the incorporation by reference in this
Registration Statement on Form S-3 filed pursuant to Rule 462(b) of the Securities Act of 1933 of the reference to our firm
under the caption &#8220;Experts&#8221; included in the Registration Statement on Form S-3 (No. 333-255184) and related
Prospectus dated July 12, 2018 and the related Prospectus Supplement dated May 21, 2020 for the registration of its common stock and warrants to purchase common stock, and to the
incorporation by reference of our reports dated March 12, 2020, with respect to the financial statements of Geron Corporation
and the effectiveness of internal control over financial reporting of Geron Corporation, included in its Annual Report (Form
10-K) for the year ended December 31, 2019 filed with the Securities and Exchange Commission.</FONT></P>
<P style="TEXT-ALIGN: left"><FONT size=2 face="Times New Roman">/s/ ERNST &amp; YOUNG LLP</FONT></P>
<P style="TEXT-ALIGN: left"><FONT size=2 face="Times New Roman">Redwood City, California<BR></FONT><FONT size=2 face="Times New Roman">May 21, 2020</FONT></P>
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