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INCOME TAXES - EFFECTIVE INCOME TAX RATE (Details)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Effective Income Tax Rate Continuing Operations Tax Rate Reconciliation [Abstract]      
Tax at statutory rate 21.00% 21.00% 21.00%
State income tax, net of federal benefit 9.00% 6.90% 12.20%
Federal and state tax credits 5.70% 5.30% 4.00%
Stock-based compensation (1.20%) (0.50%) (0.80%)
Net operating loss not benefitted (5.40%) (6.90%) (5.80%)
Other (0.20%) (0.30%) (0.20%)
Change in valuation allowance (28.90%) (25.50%) (30.40%)
Effective tax rate 0.00% 0.00% 0.00%