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v3.22.1

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 3 Months Ended
--- | ---
Mar. 31, 2022 | Mar. 31, 2021
Cash flows from operating activities: |  |
Net loss | $ (30,098) | $ (27,824)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation and amortization | 57 | 48
Accretion and amortization on investments, net | 196 | 416
Amortization of debt issuance costs/debt discounts | 349 | 180
Gain on sales of equity investment |  | (1,233)
Stock-based compensation for services by non-employees | 15 | 25
Stock-based compensation for employees and directors | 1,692 | 1,794
Amortization of right-of-use assets | 141 | 132
Changes in assets and liabilities: |  |
Current and noncurrent assets | (7,293) | (3,757)
Current and noncurrent liabilities | 967 | (2,515)
Net cash used in operating activities | (33,974) | (32,734)
Cash flows from investing activities: |  |
Purchases of property and equipment | (50) | (10)
Purchases of marketable securities | (18,104) | (25,122)
Proceeds from maturities of marketable securities | 48,581 | 61,621
Proceeds from sales of equity investment |  | 1,594
Net cash provided by investing activities | 30,427 | 38,083
Cash flows from financing activities: |  |
Proceeds from issuances of common stock from equity plans |  | 17
Proceeds from issuances of common stock from at market offerings, net of paid issuance costs |  | 16,234
Proceeds from exercise of warrants |  | 12
Net cash provided by financing activities |  | 16,263
Effect of exchange rates on cash, cash equivalents and restricted cash | 1 |
Net change in cash, cash equivalents and restricted cash | (3,547) | 21,612
Cash, cash equivalents and restricted cash at the beginning of the period | 35,235 | 10,288
Cash, cash equivalents and restricted cash at the end of the period | $ 31,689 | $ 31,900

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- Definition The sum of the periodic adjustments of the differences between securities' face values and purchase prices that are charged against earnings. This is called accretion if the security was purchased at a discount and amortization if it was purchased at premium. As a noncash item, this element is an adjustment to net income when calculating cash provided by or used in operations using the indirect method. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -URI http://asc.fasb.org/extlink&oid=123570139&loc=d3e3602-108585 + Details
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- Definition Amount of amortization expense attributable to debt discount (premium) and debt issuance costs. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=123570139&loc=d3e3602-108585 Reference 2: http://www.xbrl.org/2003/role/exampleRef -Publisher FASB -Name Accounting Standards Codification -Topic 470 -SubTopic 20 -Section 55 -Paragraph 69E -URI http://asc.fasb.org/extlink&oid=123466577&loc=SL123495743-112612 Reference 3: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 835 -SubTopic 30 -Section 45 -Paragraph 3 -URI http://asc.fasb.org/extlink&oid=124435984&loc=d3e28555-108399 Reference 4: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 470 -SubTopic 20 -Section 50 -Paragraph 1F -Subparagraph (b)(2) -URI http://asc.fasb.org/extlink&oid=123466505&loc=SL123495355-112611 Reference 5: http://www.xbrl.org/2003/role/exampleRef -Publisher FASB -Name Accounting Standards Codification -Topic 470 -SubTopic 20 -Section 55 -Paragraph 69F -URI http://asc.fasb.org/extlink&oid=123466577&loc=SL123495745-112612 + Details
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