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v3.22.2.2

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) | 9 Months Ended
--- | ---
Sep. 30, 2022 | Sep. 30, 2021
Cash flows from operating activities: |  |
Net loss | $ (99,266,000) | $ (84,095,000)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation and amortization | 208,000 | 154,000
Accretion and amortization on investments, net | (9,000) | 1,137,000
Amortization of debt issuance costs/debt discount | 1,103,000 | 627,000
Gain on sales of equity investment |  | (1,233,000)
Stock-based compensation for services by non-employees | 140,000 | 71,000
Stock-based compensation for employees and directors | 5,813,000 | 5,775,000
Amortization of right-of-use assets | 431,000 | 403,000
Changes in assets and liabilities: |  |
Current and noncurrent assets | (24,506,000) | (3,363,000)
Current and noncurrent liabilities | 23,888,000 | 7,136,000
Net cash used in operating activities | (92,198,000) | (73,388,000)
Cash flows from investing activities: |  |
Purchases of property and equipment | (291,000) | (104,000)
Purchases of marketable securities | (97,336,000) | (116,482,000)
Proceeds from maturities of marketable securities | 140,706,000 | 178,574,000
Proceeds from sales of equity investment |  | 1,594,000
Net cash provided by investing activities | 43,079,000 | 63,582,000
Cash flows from financing activities: |  |
Proceeds from issuances of common stock from equity plans | 1,962,000 | 204,000
Proceeds from issuance of common stock and warrants in public offering, net of paid issuance costs | 69,916,000 |
Proceeds from issuances of common stock from at market offerings, net of paid issuance costs |  | 16,234,000
Proceeds from exercise of warrants | 3,638,000 | 2,479,000
Proceeds from debt financing |  | 10,000,000
Debt discount and issuance costs for debt financing | (175,000) |
Net cash provided by financing activities | 75,341,000 | 28,917,000
Net effect of unrealized losses and exchange rates on cash, cash equivalents and restricted cash | 10,000 |
Net change in cash, cash equivalents and restricted cash | 26,232,000 | 19,111,000
Cash, cash equivalents and restricted cash at the beginning of the period | 35,235,000 | 10,288,000
Cash, cash equivalents and restricted cash at the end of the period | $ 61,467,000 | $ 29,399,000

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