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INCOME TAXES - DEFERRED TAXES (Details) - USD ($) | 12 Months Ended
--- | ---
Dec. 31, 2022 | Dec. 31, 2021
Significant components of deferred tax assets |  |
Net operating loss carryforwards | $ 254,500,000 | $ 241,300,000
Federal and state tax credits | 56,700,000 | 49,600,000
Capitalized research and development | 21,800,000 | 6,900,000
Stock-based compensation | 10,800,000 | 10,200,000
Operating lease liabilities | 1,300,000 | 1,400,000
Other | 5,600,000 | 2,600,000
Total deferred tax assets | 350,700,000 | 312,000,000
Less: valuation allowance | (349,600,000) | (310,700,000)
Net deferred tax assets | 1,100,000 | 1,300,000
Operating leases, right-of-use assets | (1,100,000) | (1,300,000)
Total deferred tax liabilities | (1,100,000) | (1,300,000)
Valuation allowance |  |
Increase (decrease) in valuation allowance | $ 38,900,000 | $ 33,500,000

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