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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022
Cash flows from operating activities:
Net loss	$ (38,122)	$ (30,098)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	99	57
Accretion and amortization on investments, net	(1,727)	196
Amortization of debt issuance costs/debt discounts	242	349
Stock-based compensation for services by non-employees	112	15
Stock-based compensation for employees and directors	2,961	1,692
Amortization of right-of-use assets	152	141
Changes in assets and liabilities:
Current and noncurrent assets	1,915	(7,293)
Current and noncurrent liabilities	(11,997)	967
Net cash used in operating activities	(46,365)	(33,974)
Cash flows from investing activities:
Purchases of property and equipment	(372)	(50)
Purchases of marketable securities	(241,611)	(18,104)
Proceeds from maturities of marketable securities	63,250	48,581
Net cash (used in) provided by investing activities	(178,733)	30,427
Cash flows from financing activities:
Proceeds from issuances of common stock from equity plans	7,875
Proceeds from issuance of common stock from public offering and pre-funded warrant, net of paid issuance costs	213,337
Proceeds from exercise of warrants	59,835
Net cash provided by financing activities	281,047
Effect of exchange rates on cash, cash equivalents and restricted cash	(16)	1
Net increase (decrease) in cash, cash equivalents and restricted cash	55,933	(3,546)
Cash, cash equivalents and restricted cash at the beginning of the period	57,209	35,235
Cash, cash equivalents and restricted cash at the end of the period	$ 113,142	$ 31,689

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