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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
 6 Months Ended
Jun. 30, 2023
Jun. 30, 2022
Cash flows from operating activities:    
Net loss $ (87,349) $ (58,215)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 220 129
Accretion and amortization on investments, net (4,963) 304
Amortization of debt issuance costs/debt discounts 487 704
Stock-based compensation for services by non-employees 211 28
Stock-based compensation for employees and directors 6,906 3,750
Amortization of right-of-use assets 306 285
Changes in assets and liabilities:    
Current and noncurrent assets 2,411 (5,507)
Current and noncurrent liabilities 5,805 (4,094)
Net cash used in operating activities (75,966) (62,616)
Cash flows from investing activities:    
Purchases of property and equipment (574) (120)
Purchases of marketable securities (355,718) (57,049)
Proceeds from maturities of marketable securities 133,115 90,406
Net cash (used in) provided by investing activities (223,177) 33,237
Cash flows from financing activities:    
Proceeds from issuances of common stock from equity plans 8,448 761
Proceeds from issuance of common stock from public offering and pre-funded warrant, net of paid issuance costs 213,337 69,916
Proceeds from exercise of warrants 77,602  
Debt discount and issuance costs for debt financing   (114)
Net cash provided by financing activities 299,387 70,563
Effect of exchange rates on cash, cash equivalents and restricted cash (15) 2
Net increase in cash, cash equivalents and restricted cash 229 41,186
Cash, cash equivalents and restricted cash at the beginning of the period 57,209 35,235
Cash, cash equivalents and restricted cash at the end of the period $ 57,438 $ 76,421