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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 9 Months Ended
--- | ---
Sep. 30, 2024 | Sep. 30, 2023
Cash flows from operating activities: |  |
Net loss | $ (149,220) | $ (132,154)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation and amortization | 404 | 328
Accretion and amortization on investments, net | (7,281) | (8,335)
Amortization of debt issuance costs/debt discounts | 1,894 | 742
Stock-based compensation for services by non-employees | 122 | 650
Stock-based compensation for employees and directors | 24,392 | 14,110
Amortization of right-of-use assets | 501 | 464
Changes in assets and liabilities: |  |
Inventory | (20,283) |
Accounts receivable, net | (28,007) |
Prepaid expenses, interest receivable and other assets | (1,842) | (13,694)
Current and noncurrent liabilities | 4,647 | 11,084
Net cash used in operating activities | (174,673) | (126,805)
Cash flows from investing activities: |  |
Purchases of property and equipment | (821) | (766)
Purchases of marketable securities | (292,141) | (459,727)
Proceeds from maturities of marketable securities | 290,469 | 232,602
Net cash used in investing activities | (2,493) | (227,891)
Cash flows from financing activities: |  |
Proceeds from issuances of common stock from equity plans | 26,696 | 9,492
Proceeds from issuance of common stock from public offering and pre-funded warrant, net of paid issuance costs | 140,729 | 213,337
Proceeds from exercise of warrants | 418 | 105,912
Proceeds from employee stock purchase plan | 366 |
Net cash provided by financing activities | 168,209 | 328,741
Effect of exchange rates on cash, cash equivalents and restricted cash | 17 | (9)
Net increase in cash, cash equivalents and restricted cash | (8,940) | (25,964)
Cash, cash equivalents and restricted cash at the beginning of the period | 71,138 | 57,209
Cash, cash equivalents and restricted cash at the end of the period | $ 62,198 | $ 31,245

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