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CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($)
$ in Thousands
Total
Common Stock
Additional Paid-In Capital
Accumulated Deficit
Accumulated Other Comprehensive Gain (Loss)
Balances at Dec. 31, 2022 $ 79,998 $ 390 $ 1,493,469 $ (1,413,642) $ (219)
Balances (in shares) at Dec. 31, 2022   390,262,524      
Increase (Decrease) in Stockholders' Equity          
Net loss (38,122)     (38,122)  
Other comprehensive income (loss) 75       75
Foreign currency translation adjustment (16)       (16)
Issuances of common stock and pre-funded warrant to purchase common stock in public offering, net of issuance costs 213,337 $ 68 213,269    
Issuances of common stock and pre-funded warrant to purchase common stock in public offering, net of issuance costs (in shares)   68,007,741      
Issuances of common stock in connection with exercise of warrants 59,835 $ 45 59,790    
Issuances of common stock in connection with exercise of warrants (in shares)   44,983,193      
Stock-based compensation related to issuance of common stock and options for services 112 $ 1 111    
Stock-based compensation related to issuance of common stock and options for services (in shares)   9,360      
Issuance of common stock under equity plans 7,875 $ 5 7,870    
Issuance of common stock under equity plans (in shares)   5,469,028      
Stock-based compensation for equity-based awards to employees and directors 2,961   2,961    
Balances at Mar. 31, 2023 326,055 $ 509 1,777,470 (1,451,764) (160)
Balances (in shares) at Mar. 31, 2023   508,731,846      
Balances at Dec. 31, 2022 79,998 $ 390 1,493,469 (1,413,642) (219)
Balances (in shares) at Dec. 31, 2022   390,262,524      
Increase (Decrease) in Stockholders' Equity          
Net loss (132,154)        
Balances at Sep. 30, 2023 290,614 $ 542 1,836,818 (1,545,796) (950)
Balances (in shares) at Sep. 30, 2023   542,479,666      
Balances at Mar. 31, 2023 326,055 $ 509 1,777,470 (1,451,764) (160)
Balances (in shares) at Mar. 31, 2023   508,731,846      
Increase (Decrease) in Stockholders' Equity          
Net loss (49,227)     (49,227)  
Other comprehensive income (loss) (786)       (786)
Foreign currency translation adjustment 1       1
Issuances of common stock in connection with exercise of warrants 17,767 $ 13 17,754    
Issuances of common stock in connection with exercise of warrants (in shares)   12,842,857      
Stock-based compensation related to issuance of common stock and options for services 99   99    
Stock-based compensation related to issuance of common stock and options for services (in shares)   6,327      
Issuance of common stock under equity plans 573   573    
Issuance of common stock under equity plans (in shares)   361,074      
Stock-based compensation for equity-based awards to employees and directors 3,945   3,945    
Balances at Jun. 30, 2023 298,427 $ 522 1,799,841 (1,500,991) (945)
Balances (in shares) at Jun. 30, 2023   521,942,104      
Increase (Decrease) in Stockholders' Equity          
Net loss (44,805)     (44,805)  
Other comprehensive income (loss) (11)       (11)
Foreign currency translation adjustment 6       6
Issuances of common stock in connection with exercise of warrants 440   440    
Issuances of common stock in connection with exercise of warrants (in shares)   9,581      
Stock-based compensation related to issuance of common stock and options for services 28,309 $ 19 28,290    
Stock-based compensation related to issuance of common stock and options for services (in shares)   19,523,808      
Issuance of common stock under equity plans 1,044 $ 1 1,043    
Issuance of common stock under equity plans (in shares)   1,004,173      
Stock-based compensation for equity-based awards to employees and directors 7,204   7,204    
Balances at Sep. 30, 2023 290,614 $ 542 1,836,818 (1,545,796) (950)
Balances (in shares) at Sep. 30, 2023   542,479,666      
Balances at Dec. 31, 2023 247,949 $ 545 1,844,988 (1,597,769) 185
Balances (in shares) at Dec. 31, 2023   544,912,215      
Increase (Decrease) in Stockholders' Equity          
Net loss (55,390)     (55,390)  
Other comprehensive income (loss) (448)       (448)
Foreign currency translation adjustment (10)       (10)
Issuances of common stock and pre-funded warrant to purchase common stock in public offering, net of issuance costs 141,000 $ 42 140,958    
Issuances of common stock and pre-funded warrant to purchase common stock in public offering, net of issuance costs (in shares)   41,999,998      
Issuances of common stock in connection with exercise of warrants 49   49    
Issuances of common stock in connection with exercise of warrants (in shares)   37,640      
Stock-based compensation related to issuance of common stock and options for services 92   92    
Stock-based compensation related to issuance of common stock and options for services (in shares)   2,462      
Issuance of common stock under equity plans 6,749 $ 4 6,745    
Issuance of common stock under equity plans (in shares)   4,211,493      
Stock-based compensation for equity-based awards to employees and directors 4,877   4,877    
Balances at Mar. 31, 2024 344,868 $ 591 1,997,709 (1,653,159) (273)
Balances (in shares) at Mar. 31, 2024   591,163,808      
Balances at Dec. 31, 2023 247,949 $ 545 1,844,988 (1,597,769) 185
Balances (in shares) at Dec. 31, 2023   544,912,215      
Increase (Decrease) in Stockholders' Equity          
Employee stock purchases 366 $ 366      
Employee stock purchases (in shares)   201,052      
Balances at Jun. 30, 2024 306,695 $ 601 2,027,173 (1,720,542) (537)
Balances (in shares) at Jun. 30, 2024   601,048,108      
Balances at Dec. 31, 2023 247,949 $ 545 1,844,988 (1,597,769) 185
Balances (in shares) at Dec. 31, 2023   544,912,215      
Increase (Decrease) in Stockholders' Equity          
Net loss (149,220)        
Balances at Sep. 30, 2024 292,284 $ 603 2,037,653 (1,746,989) 1,017
Balances (in shares) at Sep. 30, 2024   603,102,073      
Balances at Mar. 31, 2024 344,868 $ 591 1,997,709 (1,653,159) (273)
Balances (in shares) at Mar. 31, 2024   591,163,808      
Increase (Decrease) in Stockholders' Equity          
Net loss (67,383)     (67,383)  
Other comprehensive income (loss) (243)       (243)
Foreign currency translation adjustment (21)       (21)
Offering expenses (271)   (271)    
Issuances of common stock in connection with exercise of warrants 365   365    
Issuances of common stock in connection with exercise of warrants (in shares)   281,211      
Stock-based compensation related to issuance of common stock and options for services 16 $ 1 15    
Stock-based compensation related to issuance of common stock and options for services (in shares)   1,916      
Issuance of common stock under equity plans 16,373 $ 9 16,364    
Issuance of common stock under equity plans (in shares)   9,400,121      
Stock-based compensation for equity-based awards to employees and directors 12,625   12,625    
Balances at Jun. 30, 2024 306,695 $ 601 2,027,173 (1,720,542) (537)
Balances (in shares) at Jun. 30, 2024   601,048,108      
Increase (Decrease) in Stockholders' Equity          
Net loss (26,447)     (26,447)  
Other comprehensive income (loss) 1,507       1,507
Foreign currency translation adjustment 47       47
Issuances of common stock in connection with exercise of warrants 4   4    
Issuances of common stock in connection with exercise of warrants (in shares)   3,080      
Stock-based compensation related to issuance of common stock and options for services 14   14    
Stock-based compensation related to issuance of common stock and options for services (in shares)   1,767      
Issuance of common stock under equity plans 3,574 $ 2 3,572    
Issuance of common stock under equity plans (in shares)   2,049,118      
Stock-based compensation for equity-based awards to employees and directors 6,890   6,890    
Balances at Sep. 30, 2024 $ 292,284 $ 603 $ 2,037,653 $ (1,746,989) $ 1,017
Balances (in shares) at Sep. 30, 2024   603,102,073