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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2025
Mar. 31, 2024
Cash flows from operating activities:    
Net loss $ (19,835) $ (55,390)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 131 111
Accretion and amortization on investments, net (2,210) (2,367)
Amortization of debt issuance costs/debt discounts 253 802
Non-cash interest expense on liabilities for sales of future royalties 4,801 0
Payment on Royalty agreement (3,682) 0
Stock-based compensation for services by non-employees 15 92
Stock-based compensation for employees and directors 7,408 4,877
Amortization of right-of-use assets 177 164
Increase in allowance for doubtful accounts 131 0
Changes in assets and liabilities:    
Inventory (17,508) 0
Accounts receivable, net 4,649 0
Prepaid expenses, interest receivable and other assets (1,688) (819)
Current and noncurrent liabilities (20,621) (9,723)
Net cash used in operating activities (47,979) (62,253)
Cash flows from investing activities:    
Purchases of property and equipment 32 (615)
Purchases of marketable securities (46,477) (65,618)
Proceeds from maturities of marketable securities 98,884 100,440
Net cash provided by investing activities 52,439 34,207
Cash flows from financing activities:    
Proceeds from issuances of common stock from equity plans 256 6,749
Proceeds from issuance of common stock from offering and pre-funded warrant, net of paid issuance costs 0 141,000
Proceeds from exercise of warrants 0 49
Net cash provided by financing activities 256 147,798
Effect of exchange rates on cash, cash equivalents and restricted cash 18 (10)
Net increase in cash, cash equivalents and restricted cash 4,734 119,742
Cash, cash equivalents and restricted cash at the beginning of the period 80,876 71,138
Cash, cash equivalents and restricted cash at the end of the period $ 85,610 $ 190,880