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CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($) $ in Thousands | Total | Common Stock | Additional Paid-In Capital | Accumulated Deficit | Accumulated Other Comprehensive Gain (Loss)
--- | --- | --- | --- | --- | ---
Balance at beginning of period (in shares) at Dec. 31, 2023 |  | 544,912,215 |  |  |
Balance at beginning of period at Dec. 31, 2023 | $ 247,949 | $ 545 | $ 1,844,988 | $ (1,597,769) | $ 185
Increase (Decrease) in Stockholders' Equity |  |  |  |  |
Net loss | (55,390) |  |  | (55,390) |
Other comprehensive income (loss) | (448) |  |  |  | (448)
Foreign currency translation adjustment | (10) |  |  |  | (10)
Issuance of common stock under equity plans (in shares) |  | 4,211,493 |  |  |
Issuances of common stock under equity plans | 6,749 | $ 4 | 6,745 |  |
Stock-based compensation related to issuances of common stock and options in exchange for services (in shares) |  | 2,462 |  |  |
Stock-based compensation related to issuances of common stock and options in exchange for services | 92 |  | 92 |  |
Issuance of common stock and pre-funded warrant to purchase common stock in public offering, net of issuance costs of $9,000 (in shares) |  | 41,999,998 |  |  |
Issuance of common stock and pre-funded warrant to purchase common stock in public offering, net of issuance costs of $9,000 | 141,000 | $ 42 | 140,958 |  |
Issuances of common stock in connection with exercise of warrants (in shares) |  | 37,640 |  |  |
Issuance of common stock in connection with exercise of warrants | 49 |  | 49 |  |
Stock-based compensation for equity-based awards to employees and directors | 4,877 |  | 4,877 |  |
Balance at end of period (in shares) at Mar. 31, 2024 |  | 591,163,808 |  |  |
Balance at end of period at Mar. 31, 2024 | 344,868 | $ 591 | 1,997,709 | (1,653,159) | (273)
Balance at beginning of period (in shares) at Dec. 31, 2023 |  | 544,912,215 |  |  |
Balance at beginning of period at Dec. 31, 2023 | 247,949 | $ 545 | 1,844,988 | (1,597,769) | 185
Increase (Decrease) in Stockholders' Equity |  |  |  |  |
Net loss | (149,220) |  |  |  |
Foreign currency translation adjustment | 17 |  |  |  |
Balance at end of period (in shares) at Sep. 30, 2024 |  | 603,102,073 |  |  |
Balance at end of period at Sep. 30, 2024 | 292,284 | $ 603 | 2,037,653 | (1,746,989) | 1,017
Balance at beginning of period (in shares) at Mar. 31, 2024 |  | 591,163,808 |  |  |
Balance at beginning of period at Mar. 31, 2024 | 344,868 | $ 591 | 1,997,709 | (1,653,159) | (273)
Increase (Decrease) in Stockholders' Equity |  |  |  |  |
Net loss | (67,383) |  |  | (67,383) |
Other comprehensive income (loss) | (243) |  |  |  | (243)
Foreign currency translation adjustment | (21) |  |  |  | (21)
Issuance of common stock under equity plans (in shares) |  | 9,400,121 |  |  |
Issuances of common stock under equity plans | 16,373 | $ 9 | 16,364 |  |
Stock-based compensation related to issuances of common stock and options in exchange for services (in shares) |  | 1,916 |  |  |
Stock-based compensation related to issuances of common stock and options in exchange for services | 16 | $ 1 | 15 |  |
Offering expenses | (271) |  | (271) |  |
Issuances of common stock in connection with exercise of warrants (in shares) |  | 281,211 |  |  |
Issuance of common stock in connection with exercise of warrants | 365 |  | 365 |  |
Stock-based compensation for equity-based awards to employees and directors | 12,625 |  | 12,625 |  |
Employee stock purchases (in shares) |  | 201,052 |  |  |
Employee stock purchases | 366 |  | 366 |  |
Balance at end of period (in shares) at Jun. 30, 2024 |  | 601,048,108 |  |  |
Balance at end of period at Jun. 30, 2024 | 306,695 | $ 601 | 2,027,173 | (1,720,542) | (537)
Increase (Decrease) in Stockholders' Equity |  |  |  |  |
Net loss | (26,447) |  |  | (26,447) |
Other comprehensive income (loss) | 1,507 |  |  |  | 1,507
Foreign currency translation adjustment | 48 |  |  |  |
Foreign currency translation adjustment | 47 |  |  |  | 47
Issuance of common stock under equity plans (in shares) |  | 2,049,118 |  |  |
Issuances of common stock under equity plans | 3,574 | $ 2 | 3,572 |  |
Stock-based compensation related to issuances of common stock and options in exchange for services (in shares) |  | 1,767 |  |  |
Stock-based compensation related to issuances of common stock and options in exchange for services | 14 |  | 14 |  |
Issuances of common stock in connection with exercise of warrants (in shares) |  | 3,080 |  |  |
Issuance of common stock in connection with exercise of warrants | 4 |  | 4 |  |
Stock-based compensation for equity-based awards to employees and directors | 6,890 |  | 6,890 |  |
Balance at end of period (in shares) at Sep. 30, 2024 |  | 603,102,073 |  |  |
Balance at end of period at Sep. 30, 2024 | 292,284 | $ 603 | 2,037,653 | (1,746,989) | 1,017
Balance at beginning of period (in shares) at Dec. 31, 2024 |  | 606,387,666 |  |  |
Balance at beginning of period at Dec. 31, 2024 | 280,320 | $ 606 | 2,051,794 | (1,772,341) | 261
Increase (Decrease) in Stockholders' Equity |  |  |  |  |
Net loss | (19,835) |  |  | (19,835) |
Other comprehensive income (loss) | 55 |  |  |  | 55
Foreign currency translation adjustment | (12) |  |  |  | (12)
Exercise of Pre-Funded Warrant (in shares) |  | 30,369,830 |  |  |
Exercise of Pre-Funded Warrant | 31 | $ 31 |  |  |
Issuance of common stock under equity plans (in shares) |  | 155,349 |  |  |
Issuances of common stock under equity plans | 256 |  | 256 |  |
Stock-based compensation related to issuances of common stock and options in exchange for services (in shares) |  | 4,913 |  |  |
Stock-based compensation related to issuances of common stock and options in exchange for services | 15 |  | 15 |  |
Stock-based compensation for equity-based awards to employees and directors | 7,408 |  | 7,408 |  |
Balance at end of period (in shares) at Mar. 31, 2025 |  | 636,917,758 |  |  |
Balance at end of period at Mar. 31, 2025 | 268,238 | $ 637 | 2,059,473 | (1,792,176) | 304
Balance at beginning of period (in shares) at Dec. 31, 2024 |  | 606,387,666 |  |  |
Balance at beginning of period at Dec. 31, 2024 | 280,320 | $ 606 | 2,051,794 | (1,772,341) | 261
Increase (Decrease) in Stockholders' Equity |  |  |  |  |
Net loss | (54,638) |  |  |  |
Foreign currency translation adjustment | 65 |  |  |  |
Balance at end of period (in shares) at Sep. 30, 2025 |  | 638,355,275 |  |  |
Balance at end of period at Sep. 30, 2025 | 248,707 | $ 638 | 2,074,640 | (1,826,979) | 408
Balance at beginning of period (in shares) at Mar. 31, 2025 |  | 636,917,758 |  |  |
Balance at beginning of period at Mar. 31, 2025 | 268,238 | $ 637 | 2,059,473 | (1,792,176) | 304
Increase (Decrease) in Stockholders' Equity |  |  |  |  |
Net loss | (16,375) |  |  | (16,375) |
Other comprehensive income (loss) | (191) |  |  |  | (191)
Foreign currency translation adjustment | 4 |  |  |  | 4
Issuance of common stock under equity plans (in shares) |  | 509,072 |  |  |
Issuances of common stock under equity plans | 591 | $ 1 | 590 |  |
Stock-based compensation related to issuances of common stock and options in exchange for services (in shares) |  | 5,540 |  |  |
Stock-based compensation related to issuances of common stock and options in exchange for services | 26 |  | 26 |  |
Stock-based compensation for equity-based awards to employees and directors | 6,738 |  | 6,738 |  |
Employee stock purchases (in shares) |  | 417,369 |  |  |
Employee stock purchases | 500 |  | 500 |  |
Balance at end of period (in shares) at Jun. 30, 2025 |  | 637,849,739 |  |  |
Balance at end of period at Jun. 30, 2025 | 259,531 | $ 638 | 2,067,327 | (1,808,551) | 117
Increase (Decrease) in Stockholders' Equity |  |  |  |  |
Net loss | (18,428) |  |  | (18,428) |
Other comprehensive income (loss) | 218 |  |  |  | 218
Foreign currency translation adjustment | 73 |  |  |  | 73
Issuance of common stock under equity plans (in shares) |  | 499,834 |  |  |
Issuances of common stock under equity plans | 542 |  | 542 |  |
Stock-based compensation related to issuances of common stock and options in exchange for services (in shares) |  | 5,702 |  |  |
Stock-based compensation related to issuances of common stock and options in exchange for services | 29 |  | 29 |  |
Stock-based compensation for equity-based awards to employees and directors | 6,742 |  | 6,742 |  |
Balance at end of period (in shares) at Sep. 30, 2025 |  | 638,355,275 |  |  |
Balance at end of period at Sep. 30, 2025 | $ 248,707 | $ 638 | $ 2,074,640 | $ (1,826,979) | $ 408

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