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REVENUE RECOGNITION
 9 Months Ended
Sep. 30, 2025
Revenue from Contract with Customer [Abstract]  
REVENUE RECOGNITION REVENUE RECOGNITION
Net Product Revenue
To date, our only source of product revenue has been from the U.S. sales of RYTELO, which we began shipping to our customers in June 2024. The reconciliation of gross product sales to net product sales by each significant category of gross-to-net adjustments was as follows for the three and nine months ended September 30, 2025 (in thousands):
Three Months Ended September 30,Nine Months Ended September 30,
(in thousands)
2025202420252024
Gross product revenue$60,188 $32,657 $163,374 $33,547 
Gross-to-net adjustments:
Chargebacks and customer credits(9,083)(4,002)(22,670)(4,099)
Government rebates(2,143)(364)(2,668)(375)
Sales returns and allowances(1,795)(82)(2,426)(84)
Total gross-to-net adjustments(13,021)(4,448)(27,764)(4,558)
Net product revenue$47,167 $28,209 $135,610 $28,989