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v3.21.2

Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands | 9 Months Ended
--- | ---
Sep. 30, 2021 | Sep. 30, 2020
Cash flows from operating activities |  |
Net loss | $ (173,825) | $ (86,513)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation | 722 | 317
Stock-based compensation | 33,389 | 21,213
Amortization (accretion) of premium (discount) on marketable securities | 25 | (145)
Amortization of operating lease right-of-use asset | 5,811 | 1,793
Amortization of issuance costs | 39 | 36
Changes in assets and liabilities: |  |
Prepaid expenses and other current assets | (3,228) | 1,518
Other assets | (936) | (3,654)
Accounts payable | 3,255 | 1,616
Accrued and other current liabilities | 10,547 | 7,566
Operating lease liability | 966 | (156)
Net cash used in operating activities | (123,235) | (56,409)
Cash flows from investing activities |  |
Purchase of property and equipment | (8,598) | (1,855)
Deposits on property and equipment | (43,841) | 0
Purchase of marketable securities | 0 | (86,317)
Maturities of marketable securities | 24,500 | 134,148
Net cash provided by (used in) investing activities | (27,939) | 45,976
Cash flows from financing activities |  |
Proceeds from issuance of common stock upon options exercise | 5,753 | 1,692
Payments for restricted stock units, net of taxes withheld | 0 | (206)
Proceeds from issuance of common stock pursuant to employee stock purchase plans | 305 | 0
Proceeds from sale of future royalties, net of issuance costs | 0 | 99,643
Principal payments of capital lease | 0 | (5)
Principal payments of tenant improvement allowance payable | (33) | (28)
Net cash provided by financing activities | 6,025 | 101,096
Net increase (decrease) in cash, cash equivalents and restricted cash | (145,149) | 90,663
Cash, cash equivalents and restricted cash, at beginning of period | 950,720 | 211,937
Cash, cash equivalents and restricted cash, at end of period | 805,571 | 302,600
Reconciliation of cash, cash equivalents and restricted cash to consolidated balance sheets |  |
Cash and cash equivalents | 799,247 | 291,585
Restricted cash | 6,324 | 11,015
Cash, cash equivalents and restricted cash, at end of period | 805,571 | 302,600
Supplemental disclosures of non-cash investing and financing information: |  |
Operating lease right-of-use asset obtained in exchange for operating lease liability | 583 | 75,545
Purchase of property and equipment under accounts payable and accruals | $ 10,730 | $ 1,034

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