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Commitments and Contingencies - Additional Information (Details) $ in Thousands, SFr in Millions	1 Months Ended	9 Months Ended
	Aug. 31, 2020	Sep. 30, 2021 USD ($)	Sep. 30, 2021 CHF (SFr)	Apr. 30, 2021 CHF (SFr)	Dec. 31, 2020 USD ($)
Commitments And Contingencies Disclosure [Line Items]
Operating lease right-of-use asset		$ 68,450			$ 73,672
Lease Agreement
Commitments And Contingencies Disclosure [Line Items]
Operating lease right-of-use asset		0
Lease liabilities		0
Clinical and Commercial Supply of Drug Substance | Manufacturing Agreement | Lonza
Commitments And Contingencies Disclosure [Line Items]
Annual suite fees payment | SFr				SFr 150.0
Revised estimated capital contribution | SFr				SFr 75.0
Manufacturing agreement initial term	8 years
Clinical and Commercial Supply of Drug Substance | Maximum | Manufacturing Agreement | Lonza
Commitments And Contingencies Disclosure [Line Items]
Manufacturing agreement term that can be extended	16 years
Other Assets [Member] | Manufacturing Agreement
Commitments And Contingencies Disclosure [Line Items]
Manufacturing Agreement Expense		$ 38,700	SFr 35.0

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Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 842
-SubTopic 20
-Section 45
-Paragraph 1
-Subparagraph (b)
-URI http://asc.fasb.org/extlink&oid=121603541&loc=SL77918627-209977

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-Publisher FASB
-Name Accounting Standards Codification
-Topic 842
-SubTopic 20
-Section 45
-Paragraph 1
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-URI http://asc.fasb.org/extlink&oid=121603541&loc=SL77918627-209977

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