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Collaboration and Research Service Agreements - Summary of Revenue Recognized, Unrecognized Transaction Price and Estimated Revenue Expected to be Recognized (Details) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Disaggregation of Revenue [Line Items]    
Revenue recognized $ (45,951) $ (1,075)
Novo Collaboration Agreement    
Disaggregation of Revenue [Line Items]    
Total transaction price [1] 289,036  
Revenue recognized [2] (45,377)  
Unrecognized transaction price as of September 30, 2025 243,659  
Novo Collaboration Agreement | Combined License and Research Services    
Disaggregation of Revenue [Line Items]    
Total transaction price 247,846  
Novo Collaboration Agreement | Material Right    
Disaggregation of Revenue [Line Items]    
Total transaction price $ 41,190  
[1] Comprised of the allocation of the $195.0 million one-time, non-refundable upfront payment, of which $153.8 million was allocated to the four R&D programs and manufacturing services and $41.2 million was allocated to the material right and $94.0 million of variable consideration related to estimated research and manufacturing services for the four R&D Programs.
[2] Recorded within revenue in the statement of operations and comprehensive loss for the year ended December 31, 2025, comprised of $26.8 million recognized of the one-time, non-refundable upfront payment and $18.6 million variable considerations related to estimated research services for the four R&D Programs.