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Related Parties - Additional Information (Details) - USD ($)
1 Months Ended 12 Months Ended
Dec. 31, 2024
Dec. 31, 2025
Dec. 31, 2024
Related Party Transaction [Line Items]      
Cash proceeds on shares issued   $ 0 $ 74,942,000
Third Rock Ventures | Series B Preferred Stock      
Related Party Transaction [Line Items]      
Issuance of Series B Convertible Preferred Stock( in shares)   0 12,400,000
Cash proceeds on shares issued     $ 15,300,000
Third Rock Ventures | Related Party      
Related Party Transaction [Line Items]      
General and administrative expenses     300,000
Outstanding accounts payable   $ 0  
Consulting services $ 9,500 100,000  
Accrued expenses and other current liabilities $ 100 $ 0 100
Third Rock Ventures | Interim Chief Medical Officer      
Related Party Transaction [Line Items]      
Total fees     $ 200,000
Options to purchase 23,227   23,227
Exercise price $ 2.76   $ 2.76
RA Capital | Series B Preferred Stock      
Related Party Transaction [Line Items]      
Issuance of Series B Convertible Preferred Stock( in shares)   0 12,200,000
Cash proceeds on shares issued     $ 15,000,000
Samsara BioCapital | Series B Preferred Stock      
Related Party Transaction [Line Items]      
Issuance of Series B Convertible Preferred Stock( in shares)   0 4,300,000
Cash proceeds on shares issued     $ 5,200,000